Publications by authors named "Hong-hua Guo"
Analysis of the value of long-term antiviral therapy using sequential Peg-IFN therapy and nucleos(t)ide analogues (NAs) improves the prognosis of HBV-related HCC. HBV-related HCC patients were classified into sequential therapy with Peg-IFNα-2a and NAs, and NAs therapy alone. All patients were followed up for 5 years.
View Article and Find Full Text PDF[Clinical antiviral effects of Peg-IFNa-2a in patients with chronic hepatitis B].
Zhonghua Gan Zang Bing Za Zhi
September 2011
Article Synopsis
- The study aimed to assess the antiviral effects of Peg-IFNa-2a in chronic hepatitis B patients, with 92 participants receiving weekly injections.
- Those not responding early were split into three groups: one extended treatment to 72 weeks, another combined it with nucleoside analogues, and the last continued for 48 weeks.
- Results showed that the group extending treatment had a significantly higher sustained virological response (78.3%) compared to the standard 48-week group (38.1%), and adding nucleoside analogues also improved outcomes, making personalized treatment approaches beneficial for these patients.
[Clinical antiviral effects of telbivudine in patients with chronic hepatitis B].
Zhonghua Gan Zang Bing Za Zhi
April 2010
Objective: To analyze antiviral effects of telbivudine in patients with chronic hepatitis B.
Method: 72 chronic hepatitis B patients without prior history of antiviral therapy were treated with telbivudine 600mg once daily.
Results: At week 4, 37.
[Antiviral effects of entecavir in patients with hepatitis B virus-related cirrhosis].
Zhonghua Gan Zang Bing Za Zhi
February 2010
Objective: To analyze antiviral effects of entecavir in patients with hepatitis B virus-related cirrhosis.
Methods: 104 patients of hepatitis B virus-related cirrhosis with no previous history of antiviral therapy were treated with entecavir 0.5 mg once daily.