Publications by authors named "Hong-di Xiong"

Background: Although androgenetic alopecia (AGA) is classified as a non-inflammatory alopecia, histological evidence of microinflammation has long been recognized. However, changes in the immune microenvironment, immune-related pathways and the expression of immune-related genes (IRGs) involved in AGA remain unclear.

Methods: The microarray gene expression data (GSE36169) from patients with male AGA were analyzed.

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Introduction: Although pulsed dye laser (PDL) remains the gold standard for the treatment of port-wine stains (PWS), hematoporphyrin monomethyl ether photodynamic therapy (HMME-PDT) is another treatment modality that has been shown to be effective in the treatment of PWS. This study aimed to observe the clinical efficacy and therapeutic response of HMME-PDT in the treatment of pediatric Chinese patients with PWS and to analyze the association between the efficacy of therapy and the dermoscopic features of PWS.

Methods: Pediatric patients with PWS and negative HMME skin test were enrolled between December 2017 and May 2021.

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Article Synopsis
  • HMME-PDT is a promising treatment for port-wine stains (PWSs) in adults, showing good results in a study conducted on Chinese patients.
  • The study involved 72 adult patients who underwent HMME-PDT therapy, and results showed varying levels of efficacy: 10.77% excellent, 20% good, 64.62% fair, and 4.62% with no improvement.
  • The treatment was generally safe, but some patients experienced pain and swelling; however, systematic adverse reactions were not noted.
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