Publications by authors named "Hong-bing Nie"
Previous studies have indicated that the pathogenesis of amyotrophic lateral sclerosis (ALS) is closely linked to 5-hydroxytryptamine (5-HT). To investigate this further, we administered 5-HT receptor antagonists to SOD1*G93A transgenic (ALS mouse model) and wide-type mice. This involved intraperitoneal injections of either granisetron, piboserod, or ritanserin, which inhibit the 5-HT3, 5-HT4, and 5-HT2 receptors, respectively.
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- This study investigates the relationship between bipolar disorder (BD) and the risk of stroke, finding that individuals with BD have a higher incidence and mortality rate related to stroke.
- A meta-analysis of 7 studies with over 13 million participants revealed significant hazard ratios, indicating a 43% increased risk of stroke incidence and a 54% increased risk of stroke mortality for those with BD compared to those without.
- The findings suggest bipolar disorder may be a factor in increasing stroke risk, warranting further research into its potential as a modifiable risk factor.
Background: Many studies have described the relationship between kidney stones and stroke, but the results are controversial, so we conducted this meta-analysis to estimate the relationship between kidney stones and the risk of developing stroke.
Methods: Studies were marked with a comprehensive search of PubMed, EMBASE, Google, and ISI Web of Science databases through 25 March 2020. Hazard ratios (HRs) and 95% confidence intervals (CIs) were extracted, and a random-effects model or fix-effects model was used to compute the pooled combined risk estimate.
[Study on Microbial Diversity of Peri-implantitis Subgingival by High-throughput Sequencing].
Sichuan Da Xue Xue Bao Yi Xue Ban
July 2015
Article Synopsis
- The study aimed to explore the microbial diversity associated with peri-implantitis using high-throughput sequencing methods to understand its microbiological causes.
- Researchers collected subgingival plaque samples from patients with peri-implantitis and compared them with samples from non-peri-implantitis subjects, identifying significant differences in bacterial communities.
- Key findings indicated that certain bacteria like Selenomonas and Pseudomonas were prevalent in peri-implantitis cases, while specific bacteria in healthy subjects could influence the disease, highlighting a complex relationship between oral microbial ecosystems and peri-implantitis development.*
[Study of dental caries and correlated factors of 12-year-old children in Dongxiang, Baoan and Yugu races].
Hua Xi Kou Qiang Yi Xue Za Zhi
October 2009
Article Synopsis
- The study aimed to assess dental caries and related factors among 12-year-old children from Dongxiang, Baoan, and Yugu races.
- Findings showed high caries prevalence rates: 40.52% for Dongxiang, 44.29% for Baoan, and 46.45% for Yugu, with Yugu children displaying better oral hygiene habits.
- The research highlights the need for improved oral health education and practices to combat high rates of dental caries in these communities.
[Investigation of oral health status in 3 516 undergraduate university students].
Hua Xi Kou Qiang Yi Xue Za Zhi
April 2007
Article Synopsis
- - The study assessed the oral health of 3,516 undergraduate students at Northwest University for Nationalities, revealing that nearly 48% had dental caries and an average of 1.29 decayed teeth per student.
- - Results indicated that urban students and females had higher rates of caries, while a significant 79.78% of students exhibited dental calculus; overall dental anomalies were common among the population.
- - The conclusion emphasizes the need for improved oral health practices, suggesting that universities should promote early dental examinations, preventive care, and treatments for students.