Publications by authors named "Hong-Zhen Xu"

Pneumonia is a key criterion for the severity of COVID-19. Whether COVID-19 symptoms are indicators of pneumonia in patients infected with SARS-CoV-2 Omicron variants is unclear. 6200 non-hospitalized patients with COVID-19 from three sites in three hospitals were divided into three cohorts: Cohort 1 (n = 1971, Outpatient Department), Cohort 2 (n = 1073, Emergency Department), and Cohort 3 (n = 3156, Fever Clinic).

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Purpose: The study comprehensively evaluated the prognostic roles of the platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), basophil-to-lymphocyte ratio (BLR), and eosinophil-to-lymphocyte ratio (ELR) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

Patients And Methods: Six hundred and nineteen patients with AECOPD and 300 healthy volunteers were retrospectively included into the study. The clinical characteristics of the patients with AECOPD and the complete blood counts (CBCs) of the healthy volunteers were collected.

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Background: Imperforate anus (IA) has a life-long impact on patients and their families. The caregivers of children with IA (CoCIA) might experience distress, which could be detrimental to them physically and mentally. However, there are limitations in the related studies.

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Background: To investigate clinical manifestations and factors of perioperative brain injury (PBI) after surgical repair of coarctation of the aorta (CoA) combined with other heart malformations under cardiopulmonary bypass (CPB) in children under two years.

Methods: The clinical data of 100 children undergoing CoA repair were retrospectively reviewed between January 2010 and September 2021. Univariate and multivariate analyses were performed to identify factors of PBI development.

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Aim: Postoperative pain has adverse effects on children with urological problems, including sleep disturbances, incision dehiscence, bleeding and delayed recovery. Accurate parental assessment of children's behaviours and responses could help to manage postoperative pain. We aimed to implement evidence-based practice for parental involvement in a urology ward, to increase parents' participation in children's postoperative pain management.

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Aims And Objective: To systematically evaluate the current intervention strategies of white noise alleviating procedural pain in newborns.

Methods: This review was conducted following the PRISMA guideline. Seventeen databases National Guideline Clearinghouse, up to date, Clinical Evidence, BMJ best practice, Cochrane library, OVID, PubMed, Medline, EMBASE, Web of Science, CHINHAL, Medlive, China Biology Medicine disc, Chinese Clinical Trial Registry, China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Data Knowledge Service Platform were employed, and the studies about pain-relieving with white noise in newborns published before June 2022 was included.

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Article Synopsis
  • The study aimed to explore the knowledge, attitudes, and practices (KAP) of pediatric surgical nurses about enhanced recovery after surgery (ERAS).
  • Researchers conducted a cross-sectional survey with 34 questions distributed electronically to 855 nurses across 22 hospitals in China from February to April 2021.
  • Findings indicated that there's significant room for improvement in nurses' knowledge about postoperative recovery and preoperative preparation, influenced by factors like education level, years of experience, hospital type, and regional differences.
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Background: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a multisystem autoimmune disease with small-vessel involvement. In AAV, microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA) are major clinicopathologic variants. In addition, myeloperoxidase (MPO) and proteinase 3 (PR3) are major target antigens.

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Background: Enhanced recovery after surgery strategies are increasingly implemented to improve the management of surgical patients.

Aim: To evaluate the effects of new perioperative fasting protocols in children ≥ 3 mo of age undergoing non-gastrointestinal surgery.

Methods: This prospective pilot study included children ≥ 3 mo of age undergoing non-gastrointestinal surgery at the Children's Hospital (Zhejiang University School of Medicine) from January 2020 to June 2020.

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Background: Postoperative pain has adverse effects on children after urology treatment, including sleep disturbance, incision dehiscence, bleeding, and delayed recovery. Parents, as the most direct caregivers of children, can make accurate assessments of children´s personal behaviors and responses, which is very important for the management of postoperative pain in children.

Purpose: The purpose of the current study was to develop a Parent Participation in Postoperative Pain Management Program for children in a urology ward and to evaluate its effects on children's postoperative pain scores and other outcome indicators.

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Background: Drug extravasation is a complication of totally implantable access port (TIAP) use and could cause tissue injury and sustained organ dysfunction. Therefore, the clinical management of children with TIAP is challenging.

Case Summary: This was a case of extravasation of a chemotherapeutic drug (paclitaxel) from an implantable infusion port in a 23-mo old child.

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The success of large bone defect repair with tissue engineering technology depends mainly on angiogenesis and osteogenesis. In this study, we prepared poly-caprolactone/nano-hydroxyapatite/beta-calcium phosphate (PCL/nHA/β-TCP) composite scaffolds loaded with poly-(lactic-co-glycolic acid)/nano-hydroxyapatite/collagen/heparin sodium (PLGA/nHA/Col/HS) nanofiber small vascular stent by electrospinning and hot press forming-particle leaching methods. Supramolecular electrostatic self-assembly technology was used to modify the surfaces of small vascular stents to aid in hydrophilicity and anticoagulation.

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Article Synopsis
  • The study aimed to assess how accurately Co-Cr-Mo alloy removable partial denture (RPD) frameworks can be created using selective laser melting (SLM) technology.
  • A 3D optical scanner was used to scan a plaster dental model, and the resulting data helped design and fabricate five RPD frameworks, which were then compared to the original design for accuracy.
  • The findings indicated that the created frameworks closely matched the original model with minimal deviation, showcasing the high precision of SLM technology in producing dental frameworks.
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Purpose: To evaluate the dental quality comprehensively by data model of efficacy coefficient based on the principle of multi-objective programming.

Methods: The correlation index of dental medical quality was selected by Delphi method, while the index weight was determined by the scale of the analytic hierarchy process. Then efficacy coefficient method was used to evaluate the dental quality of Shanghai Stomatological Hospital in a certain period.

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The objective of this study is to compare the myocardium protective effect of Bretschneider's histidine-tryptophan-ketoglutarate (HTK) solution versus Modified St. Thomas' (STH) solution in pediatric cardiac surgery of Tetralogy of Fallot (TOF). Seventy-seven pediatric patients of TOF who received the total surgical repair were reviewed, from January 2014 to October 2015.

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Objective: To analyze the clinical and radiological features of paragonimiasis in children and raise the awareness of this disease.

Methods: A total of 58 paragonimiasis patients were reviewed. They were 42 boys and 16 girls aged 2.

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