Risk Factors and Clinical Characterization of Cardiovascularand Cerebrovascular Events in Elderly Hemodialysis Patients.

Introduction: The purpose of this study was to assess the risk factors and clinical characteristics of cardiovascular and cerebrovascular events in elderly hemodialysis patients.

Methods: Elderly patients undergoing hemodialysis (HD) at Deqing County People's Hospital in Zhejiang, China, from May 2020 to May 2023 were enrolled in this study. They were divided into two groups depending on the occurrence of cardiovascular or cerebrovascular events: the case group and the control group.

Dietary supplements during the cold season increase rumen microbial abundance and improve rumen epithelium development in Tibetan sheep.

Livestock on the Qinghai-Tibetan Plateau are faced with extreme harsh winters and are often in negative energy balance during this period. Dietary supplementation can improve growth performance of Tibetan sheep and, consequently, we hypothesized that it would also increase microbial abundance and rumen epithelium development. To test this hypothesis, we examined the effect of feed supplementation during the cold season on rumen microbes, fermentation, epithelium development, and absorptive capability in Tibetan sheep.

A reduced incidence of digestive disorders in rabbits is associated with allelic diversity at the TLR4 locus.

Toll-like receptor 4 (TLR4) plays a fundamental role in pathogen recognition and activation of host innate immunity. In this study, we detected five coding single-nucleotide polymorphisms (cSNPs) of the TLR4 gene in New Zealand White rabbits and analyzed their associations with genetic resistance against digestive disorders based on case-control study (125 cases and 147 controls). The five cSNPs included two synonymous mutations (c.