Size-dependent dynamics and tissue-specific distribution of nano-plastics in Danio rerio: Accumulation and depuration.

Nano-plastics (NPs), defined as particles smaller than 1 µm, have emerged as a significant environmental contaminant due to their potential ecological impacts. This study explores the size-dependent dynamics and tissue-specific distribution of polystyrene nano-plastics (PS-NPs) in Danio rerio exposed to PS-NPs at an environmentally relevant concentration of 1 μg/mL for 28 days, followed by a 17-day depuration period. PS-NPs of 20, 100, 200, and 500 nm were assessed in the intestine, liver, gills, muscle, and brain using transmission electron microscopy (TEM) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS).

The size-dependence and reversibility of polystyrene nanoplastics-induced lipid accumulation in mice: Possible roles of lysosomes.

Nanoplastics (NPs) continue to accumulate in global aquatic and terrestrial systems, posing a potential threat to human health through the food chain and/or other pathways. Both in vivo and in vitro studies have confirmed that the liver is one of the main organs targeted for the accumulation of NPs in living organisms. However, whether exposure to NPs induces size-dependent disorders of liver lipid metabolism remains controversial, and the reversibility of NPs-induced hepatotoxicity is largely unknown.

Epstein-Barr virus is a promoter of lymphoma cell metastasis.

It is well-known that Epstein-Barr virus (EBV) is the promoter of cell tumourigenesis. We found that EBV is also a promoter of lymphoma cell dissemination, because we found the typical morphopathological phenomenon of cell adhesion, which confirmed that the adhesion of tumour cells was higher than that of normal cells. We also observed that tumour cells disrupted the dynamic pathological changes of vascular endothelial cells, and this made it clear that the rate of tumour cell metastasis was directly proportional to the degree of EBV infection.

Selenium nanovirus and its cytotoxicity in selenite-exposed higher living organisms.

Selenium (Se) is an essential micronutrient in living organisms, having a narrow margin between essential and potentially toxic intake/exposure. Thus, the biochemistry of Se in living organisms must be studied in-depth to determine the underlying mechanism of Se cytotoxicity. In this study, we report the emergence of selenium nanovirus (SeNVs) in selenite-exposed fish (freshwater and saltwater) and plants (dryland) and its toxicity in them.

[Characteristics of Antibiotic Resistance Genes in Downstream Areas of the Aojiang River, Fujian Province].

Many cities are located in the downstream areas of rivers. Rapid urbanization may result in drastic changes in the urban river ecosystem. Antibiotic resistant genes (ARGs) are considered to be emerging environmental pollutants, which may do harm to the health of humans and may pose a potential risk for urban ecological safety by the dissemination and enrichment of ARGs in urban rivers.

[Distribution Characteristics of Antibiotic Resistance Genes in Sika Deer Farm].

Sika deer breeding is rapidly developing in South China during the recent years; however, the impact of sika deer breeding on the abundance and diversity of antibiotic resistance genes (ARGs) in sika deer farm remains elusive. In this study, profiles of ARGs were investigated using high-throughput qPCR technique. The results showed that the abundance of ARGs varied among different samples in the following order, deer manure composting > deer manure > vegetable soil > pristine soil, and the profiles of ARGs in these samples were significantly different (<0.