Publications by authors named "Hong-Yu Zhuo"
Nasopharyngeal carcinoma (NPC) represents a highly aggressive malignant tumor. Competing endogenous RNAs (ceRNA) regulation is a common regulatory mechanism in tumors. The ceRNA network links the functions between mRNAs and ncRNAs, thus playing an important regulatory role in diseases.
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- NK/T-LAHS is a rare and severe condition linked to nasal type extranodal NK/T cell lymphoma, with an incidence of 7.1% among studied patients.
- Most patients exhibit symptoms like fever, lymph node swelling, and liver dysfunction, with only 4.8% of those with hemophagocytic syndrome surviving beyond 3 months.
- Key risk factors for developing NK/T-LAHS include bone marrow involvement, hepatosplenomegaly, and elevated LDH levels, with a proposed risk model categorizing patients into low, intermediate, or high risk for the syndrome.
The "sandwich" protocol, was first proposed by us and comprised of l-asparaginase, vincristine, and prednisone chemotherapy with radiotherapy, results in 2-year overall survival and progression-free survival rates that surpass traditional therapies for patients with newly diagnosed, stage IE-IIE, nasal type, extranodal natural killer/T-cell lymphoma. The results had been published by cancer. These patients were followed up over a median period of 67 months, for which updates and the results of prognostic factors analyses are presented.
View Article and Find Full Text PDFTesting for hepatitis B infection in prospective chemotherapy patients: a retrospective study.
World J Gastroenterol
February 2013
Aim: To estimate hepatitis B virus (HBV) infection testing rate in cancer patients before chemotherapy with a focus on HBV reactivation.
Methods: A retrospective study was conducted from January 1, 2009 to June 30, 2010. Inclusion required that patients be naïve to cancer chemotherapy but have indications for it.