Publications by authors named "Hong-Yu Miao"
Article Synopsis
- The text discusses the increasing importance of understanding cellular component interactions in biology, highlighting that existing tools have limitations as they often focus on just one type of molecule.
- A new platform called BioTriangle has been developed to address these gaps by integrating cheminformatics and bioinformatics, providing a comprehensive toolkit for analyzing various biological molecules and their interactions.
- BioTriangle is user-friendly, allowing users to easily compute molecular features and perform tasks directly through a web browser without the need for complex installations, making it accessible for research in computational biology.
Background: Molecular descriptors and fingerprints have been routinely used in QSAR/SAR analysis, virtual drug screening, compound search/ranking, drug ADME/T prediction and other drug discovery processes. Since the calculation of such quantitative representations of molecules may require substantial computational skills and efforts, several tools have been previously developed to make an attempt to ease the process. However, there are still several hurdles for users to overcome to fully harness the power of these tools.
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