Viral infection dynamics in a spatial heterogeneous environment with cell-free and cell-to-cell transmissions.

In this paper, we investigate a diffusive viral infection model in a spatial heterogeneous environment with two types of infection mechanisms and distinct dispersal rates for the susceptible and infected target cells. After establishing well-posedness of the model system, we identify the basic reproduction number and explore the properties of when the dispersal rate for infected target cells varies from zero to infinity. Moreover, we demonstrate that the basic reproduction number is a threshold parameter: the infection and virus will be cleared out if ≤ 1, while if > 1, the infection will persist and the model system admits at least one positive (chronic infection) steady state.

Global dynamics of an immunosuppressive infection model with stage structure.

In this paper, we propose an immunosuppressive infection model incorporating natural mortality of immune cells during the time lag needed for the expansion of immune cells. Starting from a stage structure model for the immune cells with various ages, we use the method of characteristic lines to derive a delay differential equation for the population of mature immune cells. Then, we use Lyapunov functional techniques to obtain the global dynamics of the model system.

c.464A>G variation in the gene is detected in a Han Chinese family.

We report two heterozygous carriers of c.464A>G variation in the gene in a Chinese pedigree. The proband with hearing loss most likely inherited the c.

Maternal genetic backgrounds contribute to the genetic susceptibility of tongue cancer patients in Hunan, central of China.

Mitochondrial DNA (mtDNA) mutations played crucial roles on affecting the susceptibility to cancer. In this study, to investigate whether mitochondrial DNA mutations contributed to the genetic susceptibility of Chinese tongue cancer patients, mtDNA control regions of 105 Chinese tongue cancer patients were amplified and sequenced, the mutations were recorded by comparing with the revised Cambridge Reference Sequence (rCRS), which were attributed to certain mtDNA haplogroups based on the specific variations motif of each patients. The Miao Chinese group (a Chinese ethnic minority) from surrounding region has no essential difference with tongue cancer group, which was taken as the matched control group with principal component analysis by taking the haplogroups frequency of 105 tongue cancer individuals and 354 healthy individuals of eight groups from the similar geographic regions as input factors.

[Research on discrimination method of vinegar varieties and brands based on the content of inorganic elements].

Classification of brands and quality of food products is a very active area with the application of chemometric classification procedures. The content of inorganic elements such as Mg, K, Pb, Zn, Fe, Mn, Ca and Cu in 32 vinegar samples was determined by atomic absorption spectrophotometer. The similarity of Chencu and Baicu as well as different brands of vinegar samples of the same kind was calculated by vector similarity analysis.