An investigation on the changes of serum CCK-8, substance P, and 5-HT in patients with post-stroke insomnia.

Background: At present, the pathogenesis of post-stroke insomnia (PSI) is still inconclusive.

Objective: To explore the changes and significance of serum cholecystokinin-8 (CCK-8), substance P (SP), and 5-hydroxytryptamine (5-HT) in patients with PSI.

Methods: Ninety-one patients with stroke were selected as the research subjects, and according to the score of the Athens Insomnia Scale (AIS), they were divided into the insomnia group and the non-insomnia group.