Publications by authors named "Hong-Yan Lu"

Background: Extensive research has examined the role of metabolism in lung disease development, yet a comprehensive literature review remains absent despite numerous publications.

Objective: This study aims to visualize and assess the advancements in research on metabolism and its role in lung diseases.

Methods: Publications from January 1, 1991, to April 30, 2024, related to lung diseases and metabolism were sourced from the Web of Science Core Collection and analyzed using CiteSpace 6.

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In recent years, the superconducting properties of materials with diamond-like structures have attracted widespread attention. The superconducting transition temperature () of most diamond-like structures is relatively low, and there has been little research on the superconductivity of ternary diamond-like materials. Here, based on first-principles calculations, we predict BCX (X = N, P) with 31 space group, and reveal that they all exhibit phonon-mediated superconductivity at ambient pressure, with range from 44.

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Bronchopulmonary dysplasia (BPD) is a severe lung disease in preterm infants, the abnormal proliferate and differentiate ability of type II epithelial cells (AEC II) is the key to the pathological basis of BPD. Mechanisms regarding abnormal AEC II in BPD remain unclear. The present work investigated the role and mechanisms of invariant natural killer T (iNKT) cells in lung disorder in BPD using public datasets, clinical samples, a hyperoxia-induced BPD mouse model and AEC II-iNKT cells transwell co-culture system.

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Article Synopsis
  • Researchers wanted to see if a treatment with dust mites called SCIT helps kids with allergic asthma and is safe to use.
  • They studied 98 children, splitting them into two groups, where one group got regular asthma medicine and the other group got both the regular medicine and SCIT for three years.
  • Results showed that kids who received SCIT had better asthma control and fewer symptoms over three years, and the treatment was mostly safe, with very few side effects.
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Due to the rapid increase in the number of spent lithium-ion batteries, there has been a growing interest in the recovery of degraded graphite. In this work, a rapid thermal shock (RTS) strategy is proposed to regenerate spent graphite for use in lithium-ion batteries. The results of structural and morphological characterization demonstrate that the graphite is well regenerated by the RTS process.

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Regulatory T cells (Tregs) constitute a specialized subset of T cells with dual immunoregulatory and modulatory functions. Recent studies have reported that Tregs mediate immune responses and regulate the development and repair processes in non-lymphoid tissues, including bone and cardiac muscle. Additionally, Tregs facilitate the repair and regeneration of damaged lung tissues.

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The deposition and intercalation of metal atoms can induce superconductivity in monolayer and bilayer graphenes. For example, it has been experimentally proved that Li-deposited graphene is a superconductor with critical temperature of 5.9 K, Ca-intercalated bilayer graphene CCaC and K-intercalated epitaxial bilayer graphene CKC are superconductors with of 2-4 K and 3.

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Article Synopsis
  • High-purity monolayer 1T'-WS has been synthesized and is theorized to be a two-dimensional superconducting material with unique properties known as Dirac cones.
  • Research indicates that applying biaxial tensile strain affects its superconducting critical temperature, which increases initially and peaks at 7.25 K when a 3% strain is applied, before decreasing again.
  • The presence of Dirac cones under tensile strain suggests that monolayer 1T'-WS is a promising candidate for further studies on superconductivity in two-dimensional Dirac materials.
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Bronchopulmonary dysplasia, a common complication of premature infants, is mainly characterized by blocked alveolarization. Proverbially, the injury of alveolar type II epithelial cells is regarded as the pathologic basis of occurrence and development of bronchopulmonary dysplasia. In the case of alveolar epithelial damage, alveolar type II epithelial cells can also differentiate to alveolar type I epithelial cells as progenitor cells.

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The discovery of highly crystalline two-dimensional (2D) superconductors provides a new alluring branch for exploring the fundamental significances. Based on first-principles calculations, we predict a new kind of 2D stable material WC, which is a semimetal but not a superconductor because of the weak electron-phonon coupling (EPC) strength. After hydrogenation, WCH possesses the intrinsic metallic properties with a large density of states (DOS) at the Fermi energy ().

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Bronchopulmonary dysplasia (BPD) is a common complication in preterm infants characterized by alveolar growth arrest. Interleukin (IL)-33 and type 2 innate lymphoid cell (ILC2) affect type II alveolar epithelial cell (AECII) differentiation in BPD mice and may cause increased lung epithelial-mesenchymal transition (EMT). Amphiregulin (AREG) can be produced by ILC2 and is associated with tissue repair.

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Article Synopsis
  • The study aimed to review the prevalence and risk factors of frailty in patients with chronic obstructive pulmonary disease (COPD) using systematic methods and meta-analysis of published studies up to September 2022.
  • The analysis included 38 articles, revealing that approximately 36% of COPD patients were frail, while 43% were classified as pre-frail, with age and COPD assessment test scores increasing the likelihood of frailty.
  • Conversely, higher education and income levels were associated with a reduced risk of frailty, highlighting various influencing factors related to this condition in COPD patients.
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Based on the favorable ionic conductivity and structural stability, sodium superionic conductor (NASICON) materials especially utilizing multivalent redox reaction of vanadium are one of the most promising cathodes in sodium-ion batteries (SIBs). To further boost their application in large-scale energy storage production, a rational strategy is to tailor vanadium with earth-abundant and cheap elements (such as Fe, Mn), reducing the cost and toxicity of vanadium-based NASICON materials. Here, the Na V Fe (PO ) (NVFP) is synthesized with highly conductive Ketjen Black (KB) by ball-milling assisted sol-gel method.

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Article Synopsis
  • The study aimed to examine the role of type 2 innate lymphoid cells (ILC2) and various interleukins (IL-33, IL-25, TSLP, IL-5, IL-13) in preterm infants with bronchopulmonary dysplasia (BPD).
  • Researchers enrolled 76 preterm infants, dividing them into a BPD group (30 infants) and a non-BPD group (46 infants), and analyzed blood samples on days 1, 7, and 14 after birth.
  • Results indicated that BPD infants had lower birth weights and gestational ages but higher levels of ILC2, IL-33, TSLP, and IL-5 by
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With the rapid development of sodium-ion batteries (SIBs), it is urgent to exploit the cathode materials with good rate capability, attractive high energy density and considerable long cycle performance. NaV(PO)(NVP), as a NASICON-type electrode material, is one of the cathode materials with great potential for application because of its good thermal stability and stable. However, NVP has the inherent problem of low electronic conductivity, and various strategies are proposed to improve it, moreover, nanotechnology or nanostructure are involved in these strategies, the construction of nanostructured active particles and nanocomposites with conductive carbon networks have been shown to be effective in improving the electrical conductivity of NVP.

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Monolayer biphenylene is a new two-dimensional (2D) carbon allotrope, which has been experimentally synthesized and theoretically predicted to show superconductivity. In this work, we investigate functionalized biphenylene with the adsorption of Li. The superconducting critical temperature () can be pushed from 0.

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Evidence points to the indispensable function of alveolar macrophages (AMs) in normal lung development and tissue homeostasis. However, the importance of AMs in bronchopulmonary dysplasia (BPD) has not been elucidated. Here, we identified a significant role of abnormal AM proliferation and polarization in alveolar dysplasia during BPD, which is closely related to the activation of the IL-33-ST2 pathway.

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Background: We report on a case of detected by metagenomics next-generation sequencing (mNGS) in a 53-year-old male patient with polymicrobial gas gangrene and successful treatment by surgery. This report raises awareness among dermatologists that when a patient is clinically suspected of a special type of pathogenic infection, the mNGS method should be preferred to identify the patient's pathogen infection as soon as possible and then take effective treatment in time to save patients' lives.

Case Summary: A 53-year-old male who worked in the aquatic market complained of redness and swelling of the lower limbs, blisters and ulcers with fever for 3 d.

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Theoretically and experimentally, MXenes consisting of Mo and C have aroused much interest due to superconductivity in their films and even monolayer forms. Here, based on first-principles calculations, we systematically calculate the electronic structure, phonon dispersion, and electron-phonon coupling (EPC) of monolayer MoC (both T- and H-phases), MoC, and MoC. The results show that H-MoC ( = 2 or 3, = 1-3) always have lower total energies than their corresponding T phase and other configurations.

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Article Synopsis
  • This study examined self-perceived burden among patients with urostomy and its relationship to their quality of life, resilience, and social support.
  • It found that a high percentage (89.8%) of these patients felt a significant burden and reported low quality of life.
  • The research concluded that enhancing resilience and social support could help alleviate this burden and improve overall quality of life, suggesting strategies for nursing interventions.
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Article Synopsis
  • Covalent organic frameworks (COFs) are gaining popularity as advanced materials due to their versatile structural designs and functional capabilities.* -
  • COFs hold promise for improving multi-valent metal ion batteries (MVMIBs), potentially serving as a better alternative to traditional lithium-ion batteries (LIBs).* -
  • This review covers the latest developments in COFs, including their design, synthesis, applications in MVMIBs, and the challenges faced in creating COF electrodes, aiming to guide future research.*
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As an allotrope of graphene, T-graphene was predicted to be an intrinsic two-dimensional (2D) superconductor with a superconducting critical temperature () of about 20.8 K [Gu , Chin. Phys.

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In recent years, rechargeable aqueous zinc-ion batteries (ZIBs) have shown extraordinary potential due to their safety, nontoxicity, sustainable zinc resources, and low price. However, the lack of suitable cathode materials hinders the development of ZIBs. Recently, layered phosphates have been widely used as cathode materials.

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Objectives: To investigate the current status of antibiotic use in very low birth weight/extremely low birth weight infants in Jiangsu Province of China, and to provide a clinical basis for the quality and improvement of antibiotic management in the neonatal intensive care unit (NICU).

Methods: A retrospective analysis was performed on the data on general conditions and antibiotic use in the very low birth weight/extremely low birth weight infants who were admitted to 15 hospitals of Jiangsu Province from January 1, 2019 to December 31, 2020. A questionnaire containing 10 measures to reduce antibiotic use was designed to investigate the implementation of these intervention measures.

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