- The study focuses on peroxynitrite (ONOO), a reactive oxygen species that is important in various cell functions and can affect health and disease.
- Researchers developed a new ratiometric fluorescent probe called BDHCA, which specifically reacts with ONOO to produce a measurable fluorescent signal.
- The BDHCA probe is selective, fast, and sensitive for ONOO detection (with a limit of 50.3 nM) and can successfully image ONOO levels in live cells and zebrafish.