Publications by authors named "Hong-Xu Li"

Article Synopsis
  • The subcellular location and movement of Toll-like receptors (TLRs) are essential for their role in immune responses and autoimmune diseases.
  • The E3 ubiquitin ligase RNF115 inhibits TLR trafficking by modifying small GTPases RAB1A and RAB13 through ubiquitination, affecting their ability to function properly.
  • The binding of 14-3-3 chaperones to RNF115 helps it localize to the endoplasmic reticulum and Golgi apparatus, which is important for managing TLR movement within the cell.
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This paper is devoted to a nonautonomous SVIR epidemic model with relapse, that is, the recurrence rate is considered in the model. The permanent of the system is proved, and the result on the existence and uniqueness of globally attractive almost periodic solution of this system is obtained by constructing a suitable Lyapunov function. Some analysis for the necessity of considering the recurrence rate in the model is also presented.

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Three undescribed bicyclo[3.2.1]octanoid neolignan glucosides, along with a known neolignan, were isolated from the leaves of Ruiz & Pav.

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Piper crocatum Ruiz & Pav. (P. crocatum), a traditional medicinal plant, has been shown to possess various pharmacological activities, including anticancer activity, antioxidant activity, antibacterial activity, anti-hyperglycemic activity, anti-allergic inflammatory activity and others.

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Article Synopsis
  • The paper introduces a pioneering multi-group SEIR epidemic model that incorporates age structure and spatial diffusion, which is unique in the field of infectious disease modeling.
  • It analytically examines key properties of the model, such as solution positivity, boundedness, and the existence of stable disease states using Lyapunov methods and graph theory.
  • The findings are supported by numerical examples, demonstrating the model's practical applicability, particularly in scenarios involving two distinct groups.
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This study identified three coumarins (-), and six moracin derivatives (-). The structures of these natural compounds were determined by the spectroscopic methods, including 1D and 2D NMR methods, and comparison with previous reported data. All of the isolated compounds were assessed for the effects on the soluble epoxide hydrolase (sEH) inhibitory activity.

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H. Lév has been reported to have some pharmacologic activities and also interested in functional cosmetics. We found that the water extract of leaves significantly inhibited tyrosinase activity and melanin formation in α-melanocyte stimulating hormone (MSH)-induced B16-F10 cells.

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Aster tataricus L.f. is a traditional Eastern Asian herbal medicine used for the relief of cough-related illnesses.

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Two new phenolic glucosides, pipercroside A and B ( and ), along with 10 known compounds were isolated from the leaves of Ruiz & Pav. Their chemical structures were elucidated through extensive spectroscopic analyses, including 1D and 2D NMR experiments and HR-ESI-MS analysis and comparison with previously reported data. All the isolated compounds were assessed for soluble epoxide hydrolase (sEH) inhibitory activity.

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The individual parts of L. including root bark, branches, leaves, and fruits are used as a cosmetic ingredient in many Asian countries. This study identified several anti-melanogenesis constituents in a 70% ethanol extract of leaves.

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A field experiment was carried out to study the effects of balanced fertilization on growth and development, yield, fruit quality and mineral content in 'Huang-guan' pear to provide a theoretical basis for the reasonable level of fertilization in pear orchards. Four treatments were arranged with 12-year old 'Huang-guan' pear trees from the same orchard: conventional fertilization (CK), low levels of N, PO and high level of S (T), medium levels of N, PO and S (T), high levels of N, PO and low level of S (T). The results showed that different treatments had little effect on the growth and development of current-year branch and leaves in the first year.

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Sanguisorba officinalis L. was well known as a traditional herbal medicine to treat inflammation and allergic skin diseases. The aim of this research was to indentify compounds with anti-allergic inflammatory property.

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JM-101 is a developed functional food formula using water extract of Chaenomeles sinensis and Phyllostachys bambusoides for anti-obesity. Standardization and quality control of herb mixture is more difficult than those of single herb. Additionally, the estimation of mixing ratio is an essential requirement for standardization.

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In this study, 19 known compounds were isolated from mulberry (Morus alba L.) leaves. The lipid accumulation inhibitory activity of the isolated compounds was investigated.

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The mechanism and electron transfer for pollutant dihydric phenol and biomolecule L-Cysteine (L-Cys) interaction in aqueous solution were studied by means of electrochemistry and UV-VIS spectrophotometry. Two forms of L-Cys, fixed on Au-electrode and free dissolved in the solution, were examined. The results showed that L-Cys of an ordered monolayer fixed on an Au electrode facilitated electron transfer and electrocatalytic redox of three isomers of dihydric phenol.

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