Publications by authors named "Hong-Xin Yang"

Article Synopsis
  • The study aimed to evaluate the effectiveness and safety of Xuebijing injection (XBJI) for treating patients with severe sepsis, using data from 418 patients over a three-year period.
  • Results showed no significant difference in 14-day mortality or hospital stay between patients treated with carbapenem alone and those given carbapenem with XBJI, although the combined treatment led to improved inflammatory markers and kidney/liver function.
  • Although XBJI did not decrease mortality, it demonstrated benefits in reducing inflammation and protecting organ function in sepsis patients.
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Objectives: Occult breast cancer (OBC) is a rare malignant breast tumor. Because of the rare cases and limited clinical experience, a huge therapeutic difference has existed all over the world and standardized treatments have yet been established.

Methods: A meta-analysis was conducted using MEDLINE and Embase databases to identify the choice of OBC surgical procedures in all studies: (1) patients undergoing axillary lymph node dissection (ALND) or sentinel lymph node biopsy (SLNB) only; (2) patients undergoing ALND with radiotherapy (RT); (3) patients undergoing ALND with breast surgery (BS); (4) patients undergoing ALND with RT and BS; and (5) patients undergoing observation or RT only.

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Objective: To compare postoperative quality of life (QOL) of patients receiving proximal gastrectomy (PG) for adenocarcinoma of gastroesophagealjunction (AEG) throughgastric tube anastomosis and traditional esophagogastrostomy.

Methods: Between January 2010 and February 2011, 112 patients were diagnosed as AEG in our hospital. All patients underwent curative operations.

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Objective: To explore the clinical efficacy and prognosis of the patients with intermediate risk gastric stromal tumor (GST).

Methods: The data of intermediate risk GST patients confirmed by pathology and immunohistochemistry at Center of Gastrointestinal Surgery, West China Hospital, Sichuan University, between January 2007 and July 2011 were collected and retrospectively analyzed. And univariate and multivariate analyses were performed to assess the efficacy of imatinib mesylate (IM) according to recurrence-free survival (RFS).

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Objective: To investigate the prognostic factors of gastrointestinal stromal tumor (GIST).

Methods: Clinical data of 349 cases of GIST patients in our hospital between January 2006 and September 2011 were analyzed retrospectively and the prognostic factors were evaluated.

Results: 335 patients underwent R0 resection and 14 with palliative resection.

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Objective: To assess the value of carbon nanoparticles which mapping sentinel lymph node (SLN) and predict the status of lymph node metastasis status in the early gastric cancer (EGC), and to explore the SLN distribution.

Methods: Forty five patients with EGC, who underwent surgical treatment, were enrolled. At the completion of exploratory laparotomy, 1 mL solution of carbon nanoparticles was injected subserosally in the gastric wall 4-6 sites around the primary tumor during surgery in all patients.

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Objective: To investigate the clinicopathological characteristics and surgical treatment of duodenal gastrointestinal stromal tumor (GIST).

Methods: Clinicopathological data of 25 cases with duodenal GIST from January 2007 to July 2011 in West China hospital were retrospectively analyzed.

Results: All the patients were identified by pathological examination without specific symptoms.

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Objective: To investigate the clinical pathological characteristics, choice of surgical therapy and postoprative complications of patients with types II and III adenocarcinoma of esophagogastric junction (AEG).

Methods: Clinical data of 112 patients with types II and III AEG who underwent intraperiteanal operations from January 2008 to July 2010 were reviewed. Amongst the patients, 77 suffered from type II AEG and 35 suffered from type III AEG; 72 underwent proximal gastrectomy and 40 underwent total gastrectomy.

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Background: The anastomosis of gastric remnant to esophagus after proximal gastrectomy is the traditional surgical treatment procedure for patients with types II and III adenocarcinoma of esophagogastric junction. However, the postoperative complications such as gastroesophageal reflux are frequent.

Aims: To assess the outcome of the intraperitoneal anastomosis of the reconstructed gastric tube to esophagus after proximal gastrectomy for types II and III adenocarcinoma of esophagogastric junction.

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To facilitate species level identification of bacteria without the requirement of presumptive identification, the paper describes a rapid identification method of bacteria by amplification and direct sequencing 16S-23S rDNA intergenic spacer regions (ISR) of the pathogens which cause the upper respiratory tract infective disease by Streptococcus and Haemophilus. Three pairs of primer targeting conserved sequences flanking the 3' end of 16S and the 5' end of 23S rRNA were used to amplify 16S~23S rRNA ISR of 7 streptococcus strains and 8 Haemophilus strains. The PCR products were separated by 1% agarose gel electrophoresis and the polymorphisms fragments were purified with the Wizard PCR Min-Prep Kit (Promega) and Protocol-SK131(Sangon).

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