Publications by authors named "Hong-Xia Ni"
Pneumocystis jirovecii is a prevalent opportunistic fungal pathogen that can lead to life-threatening Pneumocystis pneumonia in immunocompromised individuals. Given that timely and accurate diagnosis is essential for initiating prompt treatment and enhancing patient outcomes, it is vital to develop a rapid, simple, and sensitive method for P. jirovecii detection.
View Article and Find Full Text PDFEthnopharmacological Relevance: Diabetic nephropathy (DN) is a typical chronic microvascular complication of diabetes, characterized by proteinuria and a gradual decline in renal function. At present, there are limited clinical interventions aimed at preventing the progression of DN to end-stage renal disease (ESRD). However, Chinese herbal medicine presents a distinct therapeutic approach that can be effectively combined with conventional Western medicine treatments to safeguard renal function.
View Article and Find Full Text PDFArticle Synopsis
- Colorectal cancer primarily impacts older individuals, and surgical outcomes may be significantly influenced by the patient's preoperative frailty status.
- A comprehensive review of 24 studies showed that frail patients faced higher risks of mortality at 30 days, 90 days, and 1 year compared to non-frail patients, along with increased complications like the need for reoperation and extended hospital stays.
- Understanding the relationship between frailty and postoperative risks is crucial for improving surgical management and ensuring better patient outcomes in colorectal cancer surgeries.
Prevalence and genotype distribution of HPV infection among women in Ningbo, China.
Int J Gynaecol Obstet
October 2015
Article Synopsis
- The study aimed to assess the prevalence and types of HPV among women in Ningbo, China, focusing on a sample from four villages in 2012.
- Of the 1,373 participants, 13.5% tested positive for HPV, with 13% having high-risk genotypes, and the occurrence of HPV was higher among those with more severe cervical abnormalities.
- The most common HPV type identified was HPV52, and the research suggests that vaccines targeting HPV52, HPV58, HPV16, and HPV18 are essential for preventing cervical issues in Chinese women.
[Epidemiological and etiological characteristics of hand-foot-mouth disease in Ningbo, Zhejiang province, 2008-2011].
Zhonghua Liu Xing Bing Xue Za Zhi
April 2013
Article Synopsis
- The study analyzed the epidemiological characteristics of hand foot and mouth disease (HFMD) in Ningbo, China, using surveillance data from 2008 to 2011.
- A total of 37,524 cases were reported, with a significant majority in children aged 5 or younger, and the incidence was highest from April to July.
- The primary virus responsible for HFMD was identified as EV71, with distinct sub-genotypes present, while Cox A16 was also detected; overall, the disease was found to be highly endemic in the region.
Article Synopsis
- * Researchers obtained various gene sequences, including 20 whole genome sequences, showing high similarity (96%-99%) to known epidemic strains like A/California/04/2009.
- * Specific mutations were identified in the HA receptor binding site and the M2 protein sequences, indicating potential resistance to antiviral drugs and providing valuable data on H1N1 virus transmission and variation in the region.
[Analysis on influenza antibodies detection rate and infected recently among infants].
Zhongguo Yi Miao He Mian Yi
December 2009
Objective: To understand the status of infants infected with influenza viruses after switch over of dominant strain in the summer of 2006.
Methods: Two groups of infants serum were collected and to be detected the antibodies of influenza viruses which the infants experienced two peaks of influenza A H1N1 circulation in the age of 3-4 and 10-11 months old and the infants only experience one circulation in 5-6 months old.
Results: The antibody of influenza A H1N1 viruses was 31.
110 children who were given the complete course of the inactivated hepatitis A vaccine (Havrix) were followed up 10 years later. Age-matched healthy children who were not inoculated served as controls. One month after two primary injections, all children were positive for serum antibody.
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- - The study aimed to investigate the relationship between certain single nucleotide polymorphisms in the hMLH1 gene and the risk of papillary thyroid carcinoma (PTC) in Chinese Han individuals.
- - A case-control study matched 204 PTC patients with healthy controls and identified specific gene variations, finding that certain genotypes, particularly 1151TA + AA, were associated with an increased risk of PTC.
- - Factors such as a history of CT diagnosis, previous tumors, negative life events, and frequent seafood consumption were identified as risk factors for PTC, while frequent fruit consumption appeared to reduce the risk.
[Genetic characteristic of wild-type measles viruses isolated in Ningbo from 2004 to 2008].
Zhongguo Yi Miao He Mian Yi
August 2009
Article Synopsis
- The study aimed to analyze the genetic characteristics and types of measles viruses found in Ningbo city from 2004 to 2008.
- Researchers examined throat swab samples from suspected cases and identified 22 virus strains, all classified under genotype H1, using RT-PCR and sequence analysis.
- The findings indicated high genetic similarity among the virus strains, with H1a being the main strain during the epidemic, while H1b was also present.
[Levels of transition on maternal transferred measles antibody in infants in 3 cities in China].
Zhonghua Liu Xing Bing Xue Za Zhi
November 2008
Objective: To understand the epidemiological characteristics of age distribution of measles and related policies on measles vaccines (live; MV) in infants through analyzing the antibody levels of comparison in maternal-infant pairs. Transition of immunity in infants was also studied to provide theoretic basis for measles immunization strategy and to reduce the incidence of month-old infants.
Methods: In cities of Ningbo, Harbin, and Jinan from Zhejiang, Heilongjiang and Shandong provinces, data was collected from 2004 to 2007 and analyzed regarding the epidemic situation of measles.
[Association of genetic polymorphisms and haplotypes in hMLH1 and hMSH3 gene with the risk of papillary thyroid carcinoma].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
August 2008
Objective: To explore the relationship of the genetic polymorphisms and the haplotypes in hMLH1 and hMSH3 gene with the risk of papillary thyroid carcinoma (PTC) in Chinese Hans.
Methods: A hospital based 1:1 matched case-control study was carried out. The polymorphisms for 204 pairs of PTC cases and healthy controls were identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and allele specific oligonucleotide (PCR-ASO) assays.