Modeling the physiological glucose-insulin dynamic system on diabetics.

A novel mathematical model is presented to describe the dynamic behavior of plasma glucose and insulin on diabetic subjects. Though various models have been proposed to simulate the short-term (a variety of intravenous glucose or insulin injection) glucose-insulin dynamics, it is intended to construct a modified delay differential equations (DDEs) model based on the human glucose-insulin metabolic system. Five specific adjustable parameters inside the model are defined as the factors of the major physiological functions.

Modeling the physiological glucose-insulin system on normal and diabetic subjects.

This paper aims to present a mathematical model to describe the plasma glucose and insulin daily variations on normal and diabetic subjects. The proposed model consists of two delay differential equations (DDEs) where five adjustable parameters are used to characterize the respective dynamics and oscillation behavior of normal and diabetic subjects. Several clinical data tests demonstrate that the suggested model is practical to approach the daily-life glucose dynamics on normal, diabetic Type 1 and Type 2 subjects.

Application of European system for cardiac operative risk evaluation (EuroSCORE) in coronary artery bypass surgery for Taiwanese.

The applicability for Taiwanese cardiac surgery is unclear. The preliminary goal of our study was to evaluate the validity of EuroSCORE in coronary artery bypass surgery (CABG). From January 1999 to January 2004, 801 consecutive adult patients who received primary or re-operative off- and on-pump CABG in our institute were collected.