Orbital Solitary Fibrous Tumors: A 20-Year Cases Series Study in a Single Center.

Purpose: To investigate the clinical manifestations, imaging, pathology, and prognosis of orbital solitary fibrous tumors (OSFTs). In addition, the surgical incisions and the treatment outcomes were also evaluated.

Methods: A total of 89 patients with pathologically confirmed primary OSFTs were enrolled onto this study.

Clinical analysis of 2790 children with retinoblastoma: a single-center experience in China.

Background: In this study, we aimed to analyze the clinical characteristics and prognosis of children with retinoblastoma (RB) in a single center in China with a large sample collection spanning 17 years.

Methods: The clinical data of 2790 children with RB treated in Beijing Tongren Hospital from 2005 to 2021 were collected, and a retrospective analysis was conducted.

Results: The median age of the participants was 28.

Clinical Analysis of Primary Malignant Lacrimal Sac Tumors: A Case Series Study With a Comparison to the Previously Published Literature.

Purpose: To report management of a series of patients with primary malignant lacrimal sac tumors and to compare these results to the previously published literature.

Materials And Methods: A total of 27 patients with pathologically confirmed primary malignant lacrimal sac lesions were enrolled into this study. Pathological classifications, clinical characteristics, various treatment modalities and follow-up time, including tumor recurrence, were documented.

Differential expression of microRNA related to irritable bowel syndrome in a rabbit model.

Objective: This study aimed to evaluate the differential expressions of microRNAs (miRNAs) in white hair black eye (WHBE) rabbits of irritable bowel syndrome (IBS).

Methods: WHBE and Japanese white (JW) rabbits were divided into the control and IBS groups. The IBS groups were exposed to moist heat, stress and low-dose laxatives.

Analysis of post-operative endophthalmitis after pars plana vitrectomy: a 10-year experience at a single center.

Background: Endophthalmitis can be a devastating complication after pars plana vitrectomy. The incidence of postvitrectomy endophthalmitis is significantly lower than that of endophthalmitis occurring after other intraocular operations. However, normal post-operative pain and inflammation may mask endophthalmitis and lead to delayed diagnosis and grave visual consequences.

Effect of the regimen of Gaoshan Hongjingtian on the mechanism of poly (ADP-ribose) polymerase regulation of nuclear factor kappa B in the experimental diabetic retinopathy.

Background: Poly(ADP-ribose) polymerase (PARP) plays an important role in the death of retinal capillary cells in diabetic retinopathy (DR) partly via its regulation of nuclear factor kappa B (NF-κB). The current study investigated the effect of the regimen of Gaoshan Hongjingtian (RG) on the mechanism of PARP regulation of NF-κB, and demonstrated the possible impact of the RG and Gaoshan Hongjingtian (Rhodiola sachalinensis, RS) on diabetic retinopathy.

Methods: Wistar rats were made diabetic by administering streptozotocin.

[Analysis of the misdiagnosis of bilateral iridocorneal endothelial syndrome].

Objective: To analyze the misdiagnosis of bilateral iridocorneal endothelial (ICE) syndrome and the possible reasons.

Methods: The patients seen from January 1998 to December 2011 at Beijing Tongren Hospital, misdiagnosed as bilateral ICE syndrome, were analyzed retrospectively. And a literature search was performed with a Wanfang computerized database website for the case studies of bilateral ICE syndrome.

Dilemma in management of ocular medulloepithelioma in a child.

Medulloepithelioma, a rare tumor, arises from the epithelium of the medullary tube. In this article, we present a 3-year-old boy who suffered from secondary glaucoma, initially presumed the primary disease was endophthalmitis. Subconjunctival mass was later found, pathologically proved to be medulloepithelioma.