Publications by authors named "Hong-Meng Xu"

Article Synopsis
  • The study explores whether the depth of anesthesia impacts postoperative mortality, finding a significant correlation between low bispectral index (BIS) levels and increased mortality risk.
  • Analysis included data from 38,722 patients, revealing that while low BIS is linked to higher mortality after cardiac surgery, the same association was not seen for other types of surgeries.
  • The findings suggest that deep anesthesia could affect long-term mortality, particularly in cardiac surgery patients, but this effect diminished 30 days post-surgery.
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Article Synopsis
  • Mitochondrial ferritin (FtMt) regulates iron levels in cells, but its role in cancer is not fully understood due to a lack of specific gene elements.
  • Research shows FtMt inhibits the growth of neuronal tumor cells while not affecting normal fly development; higher FtMt levels are found in healthy brain tissue compared to neuroblastoma.
  • FtMt disrupts iron balance in tumor cells, leading to cell cycle arrest and increased expression of tumor suppressors, suggesting it may be a valuable target for developing therapies against neuronal cancers.
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