The study explores whether the depth of anesthesia impacts postoperative mortality, finding a significant correlation between low bispectral index (BIS) levels and increased mortality risk.
Analysis included data from 38,722 patients, revealing that while low BIS is linked to higher mortality after cardiac surgery, the same association was not seen for other types of surgeries.
The findings suggest that deep anesthesia could affect long-term mortality, particularly in cardiac surgery patients, but this effect diminished 30 days post-surgery.
Mitochondrial ferritin (FtMt) regulates iron levels in cells, but its role in cancer is not fully understood due to a lack of specific gene elements.
Research shows FtMt inhibits the growth of neuronal tumor cells while not affecting normal fly development; higher FtMt levels are found in healthy brain tissue compared to neuroblastoma.
FtMt disrupts iron balance in tumor cells, leading to cell cycle arrest and increased expression of tumor suppressors, suggesting it may be a valuable target for developing therapies against neuronal cancers.