Publications by authors named "Hong-Mei Su"
Based on metabolomics, to study the mechanism of Radix Wikstroemia indica (RWI) "Sweat soaking method" processing detoxification. The raw drug group and processed products was given raw RWI and processed RWI respectively by gavage. The control group was given the same amount of 1% sodium carboxy methyl cellulose distilled water by gavage.
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- Developing cell-impermeable Ru(II) polypyridyl complexes as photosensitizers (PS) is challenging but crucial for effective cellular uptake and low dark toxicity.
- The study demonstrated that the complex Ru(II)tris(tetramethylphenanthroline) ([Ru(TMP)]) can generate reactive singlet oxygen under visible light, enhancing its effectiveness.
- The ion-pairing method enabled significant cellular and nuclear delivery, leading to DNA damage and apoptosis in HeLa cells, while [Ru(TMP)] exhibited high photo-toxicity and low dark toxicity, making it a promising candidate for photodynamic therapy.
Bioinformatics analyses have shown that transmembrane and coiled-coil domain 1 (TMCO1) may be associated with lung adenocarcinoma. However, to the best of our knowledge, no current research has determined whether TMCO1 is involved in the development of lung adenocarcinoma. The present study aimed to identify the association between TMCO1 and lung adenocarcinoma.
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