Publications by authors named "Hong-Jiang Yang"
Objective: To investigate the relationship of KI polyomavirus (KIPyV) and WU polyomavirus (WUPyV) with acute respiratory infection in children in Tianjin, China.
Methods: A total of 3 730 nasopharyngeal secretions were collected from hospitalized children with acute respiratory infection in Tianjin Children's Hospital from January 2011 to December 2013. Viral nucleic acid was extracted, and virus infection (KIPyV and WUPyV) was determined by PCR.
[Detection and analysis of bocavirus in hospitalized children with respiratory infection].
Zhongguo Dang Dai Er Ke Za Zhi
January 2016
Article Synopsis
- - The study aimed to identify and analyze the genetic characteristics of human bocavirus (HBoV) in children suffering from acute respiratory infections in Tianjin, China, using 1,259 nasopharyngeal samples collected in 2012.
- - Results showed that 4.53% of the samples tested positive for HBoV, predominantly in children aged 6-36 months, with a peak of infections occurring in summer and instances of co-infections with other respiratory viruses.
- - Phylogenetic analysis revealed a high genetic similarity between the detected HBoV strains and known strains, indicating minimal gene sequence variations among them.
Article Synopsis
- The Type III secretion system (TTSS) in Pseudomonas aeruginosa is essential for its virulence, involving around 40 genes that serve various roles in secretion and translocation of effector proteins.
- The study focused on the Pcr2 gene within the popN operon, revealing that a mutant lacking Pcr2 has significantly impaired secretion and translocation abilities, indicating its critical involvement in these processes.
- Additionally, Pcr2 appears to function as part of a chaperone complex for the PopN protein and is secreted in a manner linked to TTSS, suggesting a role in the formation of the TTSS structure itself.
[Type III secretion study of popN- mutant of Pseudomonas aeruginosa and proteases degradation].
Sheng Wu Gong Cheng Xue Bao
September 2007
Pseudomonas aeruginosa is an important opportunistic human pathogen. It encodes many virulence factors and one of them is type III secretion system (TTSS). Effectors proteins can be delivered into host cells directly by this system, causing necrosis or apoptosis.
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