Publications by authors named "Hong-Il Ha"

In Walker's nonmetric method, the nuchal crest serves as the representative region for indicating sexual dimorphism in cranial bones. However, the accuracy of sex estimation using the nuchal crest is lower than that using other anatomical regions. Furthermore, because of the protruding processes and structurally challenging features characterized by uneven and rough surfaces, there is a lack of metric methods for sex estimation, making quantification challenging.

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Background: With the advancement of artificial intelligence technology and radiomics analysis, opportunistic prediction of osteoporosis with computed tomography (CT) is a new paradigm in osteoporosis screening. This study aimed to assess the diagnostic performance of osteoporosis prediction by the combination of autosegmentation of the proximal femur and machine learning analysis with a reference standard of dual-energy X-ray absorptiometry (DXA).

Methods: Abdomen-pelvic CT scans were retrospectively analyzed from 1,122 patients who received both DXA and abdomen-pelvic computed tomography (APCT) scan from January 2018 to December 2020.

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Objectives: To assess the resectability of pancreatic ductal adenocarcinoma (PDAC), the evaluation of tumor vascular contact holds paramount significance. This study aimed to compare the image quality and diagnostic performance of high-resolution (HR) pancreas computed tomography (CT) using an 80 kVp tube voltage and a thin slice (1 mm) for assessing PDAC resectability, in comparison with the standard protocol CT using 120 kVp.

Methods: This research constitutes a secondary analysis originating from a multicenter prospective study.

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Increasing utilization of computed tomography (CT) has raised concerns regarding CT radiation dose and technology has been developed to achieve an appropriate balance between image quality, radiation dose, and the amount of contrast material. This study was planned to evaluate the image quality and radiation dose in pancreatic dynamic computed tomography (PDCT) with 90-kVp tube voltage and reduction of the standard amount of contrast agent, compared with 100-kVp PDCT of the research hospital's convention. Total of 51 patients with both CT protocols were included.

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  • Evaluating hepatic fibrosis is critical to reduce liver-related health issues, and the study focuses on comparing two diagnostic ultrasound techniques: two-dimensional shear wave elastography (2D-SWE) and point shear wave elastography (p-SWE).
  • The study involved 87 patients who were assessed with both methods and analyzed for their diagnostic accuracy using histology as the standard.
  • Results showed that 2D-SWE had fewer unreliable measurements and outperformed p-SWE in identifying significant fibrosis and cirrhosis, indicating it is a more reliable and accurate method.
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Objective: This prospective multicenter study aimed to evaluate the diagnostic performance of 80-kVp thin-section pancreatic CT in determining pancreatic ductal adenocarcinoma (PDAC) resectability according to the recent National Comprehensive Cancer Network (NCCN) guidelines.

Methods: We prospectively enrolled surgical resection candidates for PDAC from six tertiary referral hospitals (study identifier: NCT03895177). All participants underwent pancreatic CT using 80 kVp tube voltage with 1-mm reconstruction interval.

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  • This study investigated how many times the ultrasound-guided attenuation parameter (UGAP) needs to be measured to assess liver fat levels in patients suspected of having nonalcoholic fatty liver disease.
  • It compared two protocols: one that measured UGAP six times and another that measured it twelve times.
  • The results showed that six measurements are just as effective as twelve in diagnosing various stages of hepatic steatosis, suggesting that six repetitions is sufficient for accurate evaluation.
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A 46-year-old male with alcoholic liver cirrhosis underwent a transjugular intrahepatic portosystemic shunt (TIPS) for refractory ascites. On the 9th day after the procedure, he presented with melena and decreasing hemoglobin levels. Hemobilia due to fistula formation between the right intrahepatic bile duct and right hepatic artery was suspected on computed tomography.

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Objectives: To compare the osteoporosis-predicting ability of computed tomography (CT) indexes in abdomen-pelvic CT using the proximal femur and the reliability of measurements in two- and three-dimensional analyses.

Methods: Four hundred thirty female patients (age range, 50-96 years) who underwent dual-energy X-ray absorptiometry and abdominal-pelvic CT within 1 month were retrospectively selected. The volumes of interest (VOIs) from the femoral head to the lesser trochanter and the femoral neck were expressed as 3DFemur.

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The purpose of this study was to evaluate the impact of the different region-of-interest (ROI) methods of 2-D shear wave elastography (2-D SWE) on hepatic fibrosis diagnosis. In this retrospective study, 83 patients who underwent 2-D SWE with three ROI methods (a circle ROI, a box ROI and multiple ROIs in an elastogram) and transient elastography (TE) were included. Liver stiffness (LS) was measured five times with each ROI method.

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Objectives: To evaluate the feasibility of HU histogram analysis (HUHA) to assess proximal femoral fragility fractures with respect to BMD.

Methods: This retrospective study included 137 patients with femoral fragility fractures who underwent hip CT and 137 control patients without fractures who underwent abdominal CT between January 2018 and February 2019. HUHA was calculated with the 3D volume of interest from the femoral head to the lesser trochanter.

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  • The study investigates factors related to Sudden Unexpected Death in Infancy (SUDI) across Asian and Western countries, revealing ethnic variations and the importance of culturally sensitive approaches to sleep practices.* -
  • A systematic review of 218 articles identified 84 SUDI-related factors, with sleep position, male sex, and bed-sharing being significant contributors across both cultural regions.* -
  • Despite low rates of SUDI in some societies, Asian cultures have fewer studies, highlighting sociocultural factors such as the significance of bed-sharing and varying practices surrounding infant sleep.*
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Background: Osteoporosis has increased and developed into a serious public health concern worldwide. Despite the high prevalence, osteoporosis is silent before major fragility fracture and the osteoporosis screening rate is low. Abdomen-pelvic CT (APCT) is one of the most widely conducted medical tests.

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Purpose: To evaluate the reliability of 3D image analysis and the effect of an iodine contrast agent on the computed tomography (CT) Hounsfield unit (HU) values of the proximal femur.

Materials And Methods: Fifty female patients (mean age, 61.3 years; age range, 50-79 years) who underwent both pre- and post-enhancement abdominopelvic CT scans were included in this retrospective study.

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Objective: To identify the CT findings associated with treatment failure after antibiotic therapy for acute appendicitis.

Materials And Methods: Altogether, 198 patients who received antibiotic therapy for appendicitis were identified by searching the hospital's surgery database. Selection criteria for antibiotic therapy were uncomplicated appendicitis with an appendiceal diameter equal to or less than 11 mm.

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  • The study assessed how respiratory motion affects liver stiffness measurements using different shear wave elastography (SWE) techniques and region of interest (ROI) methods.
  • It involved three operators testing four liver fibrosis phantoms while measuring stiffness under various motion settings and using two SWE techniques: point-SWE (pSWE) and 2D-SWE.
  • Results showed that while technical failures and unreliable measurements occurred mainly in moving modes, 2D-SWE was more consistent and efficient, suggesting it is better for patients who struggle with breath-holding during the procedure.
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Purpose: This study aimed to assess the technical performance of ElastQ Imaging compared with ElastPQ and to investigate the correlation between liver stiffness (LS) values obtained using these two techniques.

Methods: This retrospective study included 249 patients who underwent LS measurements using both ElastPQ and ElastQ Imaging equipped on the same machine. The applicability, repeatability (coefficient of variation [CV]), acquisition time, and LS values were compared using the chi-square or Wilcoxon signed-rank tests.

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Sudden infant death syndrome (SIDS) in Korea remains a poorly-understood subject for both professionals and the public. Recent reports have emphasized ethnic differences in SIDS rates, suggesting that making adjustments in child-rearing practices may contribute substantially to SIDS reduction. Two of the three major risk factors for SIDS-vulnerability of the infant and exogenous factors-need to be understood in particular depth due to their broad scope and sociocultural grounding.

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  • The study investigates how effective computed tomography (CT) Hounsfield unit histogram analysis (HUHA) is in predicting postoperative pancreatic fistulas (PF) in patients who underwent pancreaticoduodenectomy.
  • In a retrospective analysis of 54 patients, results showed that those with clinically relevant PFs had higher HUHA-A values and lower mean CT Hounsfield unit (CTHU) values compared to those without PFs.
  • The findings indicate a strong correlation between HUHA-A values and PF occurrence, suggesting that HUHA could be a reliable predictor for identifying patients at risk for postoperative complications.
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  • - The study aimed to compare the effectiveness of a new high-pitch dual-source chest CT (IR-HP-CT) that uses lower radiation to a traditional low-dose chest CT (LDCT) in healthy adults, showing significant outcomes in both radiation exposure and image quality.
  • - Thirty volunteers participated, each undergoing both types of scanning, and findings included a 40% reduction in size-specific dose estimation (SSDE) and 34% reduction in effective radiation dose (ED) for IR-HP-CT compared to LDCT.
  • - Results indicated that IR-HP-CT had lower image noise and improved signal-to-noise ratios (SNR) in lung areas, along with significantly reduced cardiac motion artifacts, suggesting
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Purpose: To evaluate the diagnostic performance of Hounsfield unit histogram analysis (HUHA) of precontrast abdominal-pelvic CT scans for predicting osteoporosis.

Materials And Methods: The study included 271 patients who had undergone dual X-ray absorptiometry (DXA) and abdominal-pelvic CT within 1 month. HUHA was measured using commercial 3D analysis software (Aquarius iNtuition v4.

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Purpose: Although gemcitabine plus cisplatin has been established as the standard first-line chemotherapy for patients with advanced biliary tract cancer (BTC), overall prognosis remains poor. We investigated the efficacy of a novel triplet combination of oxaliplatin, irinotecan, and S-1 (OIS) for advanced BTC.

Materials And Methods: Chemotherapy-naive patientswith histologically documented unresectable or metastatic BTC were eligible for this multicenter, single-arm phase II study.

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  • * Results showed that SA typically had a smaller appendiceal diameter and less periappendiceal fat inflammation than PA, while demonstrating similar levels of mural hyperemia on color Doppler imaging.
  • * In conclusion, SA presents with distinctive ultrasonographic features, such as a common diameter within the equivocal range and minimal fat inflammation, highlighting important differences from PA.
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  • With the aging population, the study focuses on the effectiveness of surgical treatment for elderly patients (≥80 years) diagnosed with advanced gastric cancer, which remains a controversial issue.
  • Analyzed data from 147 patients indicated that those undergoing surgical resection had significantly better 3-year overall survival rates compared to those receiving supportive care; 42.1% vs 4% for patients aged 80-85, and 36.4% vs 8% for those aged 86 and older.
  • While surgical treatment showed better prognoses particularly for patients aged 80-85, caution is advised for extreme-elderly patients (≥86 years) regarding the risks and benefits of surgery.
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Purposes: To determine the maximum tolerated dose (MTD), recommended dose (RD), and activity of combined oxaliplatin, irinotecan, and S-1 chemotherapy for metastatic or recurrent gastrointestinal (GI) cancer.

Methods: Oxaliplatin and irinotecan were administered intravenously on day 1, and S-1 was administered orally on days 1-7, every 2 weeks. This phase I study used the following dose levels for oxaliplatin/irinotecan/S-1: level 1, 85/120/60 mg/m; level 2, 85/120/80 mg/m; level 3, 85/120/100 mg/m; level 4, 85/150/100 mg/m; and level 5, 85/180/100 mg/m.

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