Publications by authors named "Hong-Hai Xia"
Article Synopsis
- Periostin (PN) is a glycoprotein linked to the potential for tumors to spread and their prognosis, which is particularly examined in hepatocellular carcinoma (HCC).
- In a study involving 71 patients, it was found that PN was expressed significantly more in HCC tissues (73.2%) compared to nearby tissues (19.7%), linking it to factors like tumor nodules, microvascular invasion, and overall cancer staging.
- The study concluded that high levels of PN in HCC correlate with increased angiogenesis and a poorer prognosis, making it a potential independent predictor for survival outcomes in patients following surgery.
In order to further research the relationship between classical swine fever virus' (CSFV) NS3 protein and the cytopathic effect (CPE) in cells infected with the CSFV, and to reveal the effect of protein NS3 on the host cells, the NS3 of CSFV Shimen strain amplified by RT-PCR was subcloned into the pEGFP-C1, named pEGFP-C1-NS3. The insert position, the size and the reading frame were correct for restriction enzyme digestion and sequence analysis. The pEGFP-C1-NS3 and pEGFP-C1 were transfected into PK-15 cells by liposome, and positive cell clones were gained by G418.
View Article and Find Full Text PDFSwine endothelial cells are commonly used as an in vitro model for studying features of the blood-brain barrier and some hemorrhagic diseases. However, primary cultures of swine cells have finite lifespans. To establish immortalized swine umbilical vein endothelial cells (SUVECs) using human telomerase reverse transcriptase (hTERT), the plasmid pCI-neo-hTERT was transfected into SUVECs by lipofection.
View Article and Find Full Text PDF