Publications by authors named "Hong-Feng Zhuang"
Stereospecific 3-Aza-Cope Rearrangement Interrupted Asymmetric Allylic Substitution-Isomerization.
Angew Chem Int Ed Engl
October 2024
Article Synopsis
- The text discusses advancements in transition-metal catalyzed asymmetric allylic substitution, particularly focusing on the challenges of directly arylating acyclic internal alkenes.
- It introduces a new method called interrupted asymmetric allylic substitution-isomerization (Int-AASI), which allows for the successful asymmetric allylic arylation of these compounds.
- The research demonstrates high enantioselectivity in producing allylic arylation products and axial chiral alkenes, supported by experimental findings and density functional theory studies to explain the observed selectivities.
This case report presents an evaluation of the clinical effects of an allogeneic amniotic cell transplant for the treatment of type 1 diabetes mellitus. A 26-year-old man with type 1 diabetes was treated with stem cells isolated from his neonatal son's amniotic membrane, collected at birth (2 × 10(7) cells). The cells, which expressed high levels of cluster of differentiation (CD) 133 and CD34 as assessed by flow cytometry, were infused into the pancreatic dorsal artery through the left femoral artery.
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