Publications by authors named "Hong-Feng Lu"

Article Synopsis
  • Global climate change greatly impacts extreme environments and species survival, but little is understood about how livestock, specifically sheep, have adapted genetically to these changes after domestication.
  • Researchers sequenced the genomes of 77 native sheep to analyze genetic adaptations across different extreme environments, such as high altitudes and arid zones.
  • The study identified candidate genes and biological pathways linked to responses to low oxygen levels and water retention, contributing valuable knowledge for future livestock breeding strategies in the context of climate change.
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The UV/ozone surface treatment was a simple and low cost hydrophilic modification method. In this paper,UV/ozone treatment is utilized to hydrophilize the surface of PDMS and the results are compared. Contact angle is applied to estimate the effect and stability of the modified surfaces.

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Atomic force microscopy (AFM) was used to investigate the self-assembly behavior of λ-DNA and histones at varying histone:DNA ratios. Without histones and at the lowest histone:DNA ratio (less than one histone per 1000 base pairs of DNA), the DNA appeared as individual (uncomplexed), double-stranded DNA molecules. At increasing histone concentrations (one histone per 500, 250 and 167 base pairs of DNA), the DNA molecules started to form extensive polygonal networks of mostly pentagons and hexagons.

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Aim: To explore the diffusion gradient b-factor that optimizes both apparent diffusion coefficient (ADC) measurement and contrast-to-noise (CNR) for assessing tumor response to transarterial chemoembolization (TACE) in a rabbit model.

Methods: Twelve New Zealand white rabbits bearing VX2 tumors in the liver were treated with TACE. Diffusion-weighted imaging (DWI) with various b values was performed using the same protocol before and 3 d after treatment with TACE.

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Aim: To explore the prognostic variables in rectal cancer patients undergoing curative total mesorectal excision and the effect of postoperative chemotherapy in advanced rectal cancer.

Methods: A total of 259 consecutive rectal cancer patients treated with curative total mesorectal excision between 1999 and 2004 were collected. p53, p21, PCNA, and CD44v6 were examined using immunohistochemistry (IHC).

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