Omentin-1 inhibits the development of benign prostatic hyperplasia by attenuating local inflammation.

Background: Benign prostatic hyperplasia (BPH) is a prevalent disease affecting elderly men, with chronic inflammation being a critical factor in its development. Omentin-1, also known as intelectin-1 (ITLN-1), is an anti-inflammatory protein primarily found in the epithelial cells of the small intestine. This study aimed to investigate the potential of ITLN-1 in mitigating BPH by modulating local inflammation in the prostate gland.

The inflammatory cytokine profiles and ocular biometric characteristics of primary angle-closure glaucoma.

Objective: To investigate the pathogenesis of primary angle-closure disease (PACG) by measuring the anatomical structures of the anterior and posterior segments of the eye and inflammatory markers in the peripheral blood.

Methods: This case-control study enrolled patients diagnosed with acute PACG (APACG) and chronic PACG (CPACG). It also enrolled control subjects without PACG.

Interactions between micro-scale oil droplets in aqueous surfactant solution determined using optical tweezers.

Hypothesis: The stability of the emulsions is crucial, which relies on a well-developed understanding of dynamic interaction forces between single dispersed droplets. In the previous studies, many interests focus on the oil droplets of size range of 20-200 µm. However, emulsion droplets with diameter below 10 µm are rarely mentioned, which is the size scale of real emulsion droplets in various applications, such as toners, spacers for liquid crystal displays, and materials in biomedical and biochemical analysis.

Temperature- and pH-sensitive core-shell nanoparticles self-assembled from poly(n-isopropylacrylamide-co-acrylic acid-co-cholesteryl acrylate) for intracellular delivery of anticancer drugs.

Temperature- and pH-sensitive amphiphilic polymer poly(N-isopropylacrylamide-co-acrylic acid-co-cholesteryl acrylate) (P(NIPAAm-co-AA-co-CHA)) has been synthesized and employed to encapsulate paclitaxel, a highly hydrophobic anticancer drug, in core-shell nanoparticles fabricated by a membrane dialysis method. The nanoparticles are spherical in shape, and their size can be made below 200 nm by varying fabrication parameters. The lower critical solution temperature (LCST) of the nanoparticles is pH-dependent.