Publications by authors named "Hong-Bo Guan"
The liver plays an important role in regulating lipid metabolism in animals. This study investigated the function and mechanism of in liver lipid metabolism in hens at the peak of egg production. The effect of on intracellular lipid content in LMH cells was evaluated by qPCR, Oil Red O staining, and detection of triglyceride (TG) and cholesterol (TC) content.
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- * The analysis included data from ten studies, revealing that mothers who experienced stress while pregnant had approximately double the odds (OR = 2.11) of having children with CHD, while those facing stressful life events had about 1.86 times higher odds (OR = 1.86).
- * No significant association was found between maternal anxiety or depression and CHD risk in offspring, highlighting a specific concern with stress and stressful events rather than other mental health issues.
Article Synopsis
- The study analyzed existing cohort research to understand the risks of gestational hypertension and preeclampsia in pregnant women using prenatal SSRIs (selective serotonin reuptake inhibitors) alone.
- A thorough review of literature revealed that women on SSRI monotherapy have a higher likelihood of developing gestational hypertension or preeclampsia compared to nonusers, with specific relative risks identified.
- The findings suggest that SSRI use during pregnancy is associated with these risks, highlighting the need for careful consideration when prescribing these medications to pregnant women.
Objective: To test the effects of human umbilical cord mesenchymal stem cell (HU-MSC) transplantation on reversing preeclampsia (PE) symptoms in a lipopolysaccharide (LPS)-induced rat PE model.
Methods: Human umbilical cord MSCs were detected, isolated, and cultured. Human umbilical cord MSC transplantation was conducted.
Article Synopsis
- This study aimed to analyze the impact of low-frequency repetitive transcranial magnetic stimulation (rTMS) on language recovery in stroke patients with aphasia by conducting a meta-analysis of relevant clinical trials published from 1965 to 2013.
- The analysis included seven studies with a total of 160 patients, revealing a significant improvement in language outcomes, specifically in areas like naming, repetition, writing, and comprehension.
- No patients reported adverse effects from rTMS, and the results indicated consistent positive effects across various language assessments, suggesting it may be a beneficial therapy for aphasia post-stroke.
Article Synopsis
- Previous studies on the relationship between having children (parity) and pancreatic cancer risk have shown mixed results, leading researchers to conduct a more thorough assessment.
- A review of existing literature identified a total of 22 studies that reported on the relative risk of pancreatic cancer in relation to parity, finding a summary relative risk of 0.86 for those with the highest parity compared to the lowest.
- The results indicate that higher parity may be linked to a reduced risk of pancreatic cancer, suggesting the need for further large-scale studies to better understand this relationship and adjust for other influencing factors.
Parity and kidney cancer risk: evidence from epidemiologic studies.
Cancer Epidemiol Biomarkers Prev
December 2013
Article Synopsis
- Observational studies show mixed results on the link between having children (parity) and kidney cancer risk, prompting a need for comprehensive analysis.
- A systematic review and meta-analysis of 14 studies (6 prospective, 8 case-control) found that having children is associated with a 23% increased risk of kidney cancer, with higher parity linked to a 36% increase.
- Overall, the findings suggest that both having children and the number of children a woman has positively correlate with an increased risk of developing kidney cancer.
Article Synopsis
- Several studies have looked at the relationship between having children (parity) and colorectal cancer (CRC) risk, but previous findings have been inconsistent and lacked a detailed assessment until now.* -
- Researchers analyzed data from eleven prospective studies and found that having children had a minimal effect on CRC risk, with a relative risk of 0.95 for those who have given birth compared to those who haven't.* -
- Overall, the study concluded that there is little evidence supporting a link between the number of children a woman has and her risk of developing colorectal cancer.*