Rigidity-Flexibility Regulation and Hard-Soft Donor Combination: Dual Strategies in Covalent Organic Frameworks Construction for Actinides/lanthanides Separation.

Separating actinides from lanthanides is essential for managing nuclear waste and promoting sustainable nuclear energy development. The recycling of transuranium elements (TRUs: Np, Pu, Am) is also significant for various nuclear technology applications. In this study, a dual strategy is introduced to designing covalent organic frameworks (COFs) that skillfully combines molecular rigidity with flexibility, integrating both hard and soft donor atoms in the synthesis of monomers.

Comparative characterization of microRNAs of Schistosoma japonicum from SCID mice and BALB/c mice: Clues to the regulation of parasite growth and development.

Schistosomiasis, caused by a parasite with a wide range of mammalian hosts, remains one of the most prevailing parasitic diseases in the world. While numerous studies have reported that the growth and reproduction of schistosomes in immunodeficient mice was significantly retarded, the underlying molecular mechanisms have yet to be revealed. In this study, we comparatively analyzed the microRNA expression of Schistosoma japonicum derived from SCID and BALB/c mice on the 35 day post-infection by high-throughput RNA sequencing as prominent morphological abnormalities had been observed in schistosomes from SCID mice when compared with those from BALB/c mice.

Strong Periodic Tendency of Trivalent Lanthanides Coordinated with a Phenanthroline-Based Ligand: Cascade Countercurrent Extraction, Spectroscopy, and Crystallography.

Phenanthroline-diamide ligands have been reported in the selective separation of actinides over Eu(III); on the contrary, relevant basic coordination chemistry studies are still limited, and extraction under actual application conditions is rarely involved. In this work, -diethyl--ditolyl-2,9-diamide-1,10-phenanthroline [Et-Tol-DAPhen ()] was applied to explore the coordination performance of lanthanides in simulative high-level liquid waste. For the first time, cascade countercurrent extraction was conducted with Et-Tol-DAPhen as the extractant, which reveals the periodic tendency of the extraction efficiency of lanthanides to decrease gradually as the atomic number increases.

Comparative Transcriptome Analyses of Derived From SCID Mice and BALB/c Mice: Clues to the Abnormality in Parasite Growth and Development.

Schistosomiasis, caused by the parasitic flatworms called schistosomes, remains one of the most prevailing parasitic diseases in the world. The prodigious oviposition of female worms after maturity is the main driver of pathology due to infection, yet our understanding about the regulation of development and reproduction of schistosomes is limited. Here, we comparatively profiled the transcriptome of recovered from SCID and BALB/c mice, which were collected 35 days post-infection, when prominent morphological abnormalities could be observed in schistosomes from SCID mice, by performing RNA-seq analysis.

Comparative Metabonomic Investigations of From SCID Mice and BALB/c Mice: Clues to Developmental Abnormality of Schistosome in the Immunodeficient Host.

The growth and development of schistosome has been affected in the immunodeficient hosts. But it remains unresolved about the molecular mechanisms involved in the development and reproduction regulation of schistosomes. This study tested and compared the metabolic profiles of the male and female worms collected from SCID mice and BALB/c mice at 5 weeks post infection using liquid chromatography tandem mass spectrometry (LC-MS/MS) platform, in which the worms from SCID mice were the investigated organisms and the worms from BALB/c mice were used as the controls.

[The Effect of Lipopolysaccharide-Induced Mouse B Cell Activation on Schistosoma japonicum Development].

Objective: To investigate the effect of lipopolysaccharide (LPS)-induced B cell activation on the development of Schistosoma japonicum.

Methods: Eighteen BALB/c nude mice deficient in T cells and 23 BALB/c SCID mice deficient in T and B cells were used in this study. Each was infected with 30 ± 1 S.

[Research progress of immunoregulation of B cells to schistosome infection].

Recent studies found that B cell subsets and their factors have double effects on anti- and aiding schistosome infection. This article summarizes the research progress of positive and negative immunoregulation of schistosome infection involving B lymphocytes, antibody and regulatory B cells (Bregs) relating cytokines (IL-10, IL-7 and TGF-β).

[Blood pressure variation of hypertensive diabetic nephropathy patients undergoing peritoneal dialysis].

Objective: To investigate the variance of blood pressure of hypertensive diabetic patients undergoing continuous ambulatory peritoneal dialysis (CAPD).

Methods: Twenty hypertensive CAPD patients older than 40 years with diabetic nephropathy (DN-PD group) and twenty patients with chronic glomerular nephritis (CGN-PD group) were recruited. Peritoneal status and dialysis adequacy of the patients in the two groups were calculated using PD Adequest.