Publications by authors named "Hong-Biao Li"
Article Synopsis
- - The systematic review aimed to assess how well combined topical and intravenous tranexamic acid (TXA) works at reducing blood loss during total knee arthroplasty (TKA) compared to using either method alone or a control.
- - A comprehensive search for relevant randomized controlled trials (RCTs) was conducted, and studies included focused on patients undergoing primary TKA, measuring outcomes such as total blood loss and the need for transfusions, while also monitoring for safety concerns like deep venous thrombosis (DVT).
- - The analysis of 15 studies involving 1,495 patients showed that the combined use of topical and intravenous TXA significantly reduced blood loss, with a mean difference indicating a considerable decrease in blood loss
Objective: To evaluate the efficacy and safety of fibrin sealant for the reduction of postoperative blood loss and transfusion requirements in patients undergoing total hip arthroplasty (THA) and total knee arthroplasty (TKA).
Methods: Electronic databases including PubMed, Embase, CENTRAL (Cochrane Controlled Trials Register), Web of Science and Google Scholar were searched from database inception to February 2016. All randomized controlled trials evaluating the efficacy and safety of topical administration of fibrin glue during primary THA or TKA were included in our meta-analysis.
Endoplasmic reticulum stress (ERS)-mediated cell apoptosis has been implicated in the development of multiple diseases such as cancer, neurodegenerative diseases and ischemic reperfusion damage. Previous studies have demonstrated the adenosine-induced apoptosis in several tumor cell lines. However, the role of ERS in adenosine-induced human hepatoma HepG2 cell apoptosis remains unclear.
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