Publications by authors named "Hong-An Zhang"

Background: Treatment of lower limb post-traumatic osteomyelitis used to be a staged process, with radical debridement of bone and soft tissues at first stage, followed by a second-stage limb reconstruction operation to restore the limb integrity. Some studies recently reported that achieving infection eradication and limb reconstruction at single-stage seems to be an effective method for lower limb infection, but a comparative study remains lacking. This study aims to compare the results of radical debridement combined with a first/second-staged osteotomy and bone transport, for the management of lower limb post-traumatic osteomyelitis.

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Background: The incidence of intramedullary infection is increasing with increased use of intramedullary fixation for long bone fractures. However, appropriate treatment for infection after intramedullary nailing is unclear. The purpose of this study was to report the results of our treatment protocol for infection after intramedullary nailing: intramedullary nail removal, local debridement, reaming and irrigation, and antibiotic-loaded calcium sulfate implantation with or without segmental bone resection and distraction osteogenesis.

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Background: Although various methods have been introduced, the management of chronic tibial osteomyelitis remains a challenge. This study aims to assess a combined treatment method, local debridement combined with antibiotic-loaded calcium sulfate implantation, for the management of the local (Cierny-Mader type III) tibial osteomyelitis.

Methods: Forty-two patients (43 limbs) with type III tibial osteomyelitis, from January 2012 to December 2018, who received the treatment method mentioned above were included in the study.

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Background: Management of chronic calcaneal osteomyelitis is challenging. At present, there is still no widely accepted, simple, and effective surgical method to eradicate the infection and prevent osteomyelitis recurrence. The objective of this study was to assess the outcomes of one-stage treatment of chronic calcaneal osteomyelitis with a shape-preserving debridement technique combined with antibiotic-loaded calcium sulphate.

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Background: Managing with diabetic foot osteomyelitis (DFO) is challenging. Even after infective bone resection and thorough debridement, DFO is still difficult to cure and has a high recurrence rate. This retrospective study aims to compare the outcomes of two treatment methods, infected bone resection combined with adjuvant antibiotic-impregnated calcium sulfate and infected bone resection alone, for the treatment of diabetic foot osteomyelitis.

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Article Synopsis
  • - The study compared the effectiveness of antibiotic-loaded calcium sulphate versus wound irrigation-suction in treating lower limb chronic osteomyelitis in adult patients from January 2011 to July 2015.
  • - Results showed that the calcium sulphate group had a significantly higher success rate in the initial operation (90.74%) compared to the irrigation group (45%), despite facing more post-surgery incision leaks.
  • - Overall, antibiotic-loaded calcium sulphate reduced infection rates and complications, and led to shorter hospital stays and less need for systemic antibiotics compared to the irrigation method.
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Objective: To compare the efficacy difference between acupotomy and acupuncture in the treatment of avascular necrosis of femoral head at the early and middle stages.

Methods: The randomized controlled prospective study method was adopted. Sixty cases of avascular necrosis of femoral head at Ficat-ArletⅠto Ⅱ stages were randomized into an acupotomy group (32 cases) and an acupuncture group (28 cases) by the third part.

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Article Synopsis
  • Tranexamic acid (TXA) is an effective antifibrinolytic agent used to reduce bleeding in total knee arthroplasty (TKA), as shown in a meta-analysis of 34 randomized controlled trials.
  • The study revealed that TXA significantly decreased total blood loss, postoperative blood loss, and the rate of blood transfusions, without affecting intraoperative blood loss.
  • TXA was found to be safe for patients, showing no significant increase in risks for deep vein thrombosis (DVT) or other complications.
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Objective: To explore the objective evaluation index of acupuncture effect through study on the differences of surface electromyography of deltoid before and after acupuncture at some specific points.

Methods: Twenty-six cases of periarthritis were treated with acupuncture at Jianyu (LI 15), Jianqian (Extra), Jianliao (TE 14) and Binao (LI 14). The treatment was given once every other day, six treatments were required.

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