Long non-coding RNAs are involved in the crosstalk between cancer-associated fibroblasts and tumor cells.

The proliferation of tumors is not merely self-regulated by the cancer cells but is also intrinsically connected to the tumor microenvironment (TME). Within this complex TME, cancer-associated fibroblasts (CAFs) are pivotal in the modulation of tumor onset and progression. Rich signaling interactions exist between CAFs and tumor cells, which are crucial for tumor regulation.

Cancer-associated fibroblast-derived exosome microRNA-21 promotes angiogenesis in multiple myeloma.

Multiple myeloma (MM) is the second most common hematological malignancy, and angiogenesis determines its progression. In the tumor microenvironment, normal fibroblasts (NFs) are transformed into cancer-associated fibroblasts (CAFs), which can promote angiogenesis. Microribonucleic acid-21 (miR-21) is highly expressed in various tumors.

Long non‑coding RNAs in multiple myeloma (Review).

Multiple myeloma (MM) is one of the three major malignancies of the hematological system in middle‑aged and older individuals. The incidence of MM increases with age and due to its drug resistance and high recurrence, MM seriously harms human health. Long non‑coding RNAs (lncRNAs) are RNA molecules with a length of >200 nt and rarely encode proteins.

The angiogenic genes predict prognosis and immune characteristics in esophageal squamous cell carcinoma: Evidence from multi-omics and experimental verification.

Esophageal squamous cell carcinomas (ESCC) is an aggressive disease with five-year overall survival (OS) <15%. The main cause is metastasis rather than local tumor, and angiogenesis plays an important role. Angiogenesis has a significant impact on tumor metastasis, treatment and prognosis.

Flower-Shaped Mg₃AlFe-CO₃ Layered Double Hydroxides Derived Adsorbents with Tunable Memory Effect for Environmental Remediation.

Herein, flower-shaped ternary layered double hydroxides (LDHs) Mg3Al1-xFex-CO3 with tunable memory effect as promising adsorbents was developed for the removal of acid red 88 anionic dye. All the samples were prepared using a co-precipitation method and were thoroughly characterized using several analytical techniques. The influence of Fe/(Al + Fe) ratio on the memory effect and dye adsorption capacity of Mg3Al1-xFex-CO3 LDHs was evaluated.

Healthcare utilization of bereaved family members following the 1999 Chi-chi earthquake: evidence from administrative data.

Objective: Strong earthquakes not only cause death and property damage, but also have continuous repercussions on the survivors' health. This study investigates the impact of the 1999 Chi-chi earthquake to understand how an earthquake disaster affects healthcare utilization differently between individuals who lost co-resident family members (victims) and those who did not (non-victims).

Methods: We utilize the household registration records from the Ministry of the Interior as well as claim data from the Bureau of National Health Insurance in Taiwan from 1998 to 2000.

Financial incentives and use of Cesarean delivery: Taiwan birth data 2003 to 2007.

Objectives: The Cesarean section (CS) rate in Taiwan has exceeded 30% since 2000. To lower the CS rate, the Bureau of National Health Insurance in Taiwan raised the payment for vaginal delivery (VD) in May 2005, and also increased the insured's copayment for elective CS in May 2006. This study clarifies the influences of these financial incentives, and explores whether the 2 policies lowered the CS rate.