Symptoms of depression and the discrepancy between implicit and explicit self-esteem.

Background And Objectives: While the role of explicit self-esteem (ESE) in depression has been well established, the relationship between implicit self-esteem (ISE) and depression is more uncertain. Recently, it has been suggested that a simultaneous consideration of both ESE and ISE may provide a more comprehensive understanding of the development and maintenance of depression than considering either ESE or ISE in isolation. The present paper tested whether the absolute discrepancy between ESE and ISE and the direction of the discrepancy are important factors to consider in relation to depressive symptoms.

Synthesis and anticancer activity of di(3-thienyl)methanol and di(3-thienyl)methane.

Di(3-thienyl)methanol (2) and di(3-thienyl)methane (3) have been synthesized and screened against the T98G (brain cancer) cell line. Treatment induced cell death (MTT and macro-colony assay), growth inhibition, cytogenetic damage (micronuclei formation), were studied as cellular response parameters. Treatment with the compounds enhanced growth inhibition and cell death in a concentration dependent manner in both T98G and HEK (normal) cell lines.