Strict air pollution control measures were conducted during the Youth Olympic Games (YOG) period at Nanjing city and surrounding areas in August 2014. This event provides a unique chance to evaluate the effect of government control measures on regional atmospheric pollution and greenhouse gas emissions. Many previous studies have observed significant reductions of atmospheric pollution species and improvement in air quality, while no study has quantified its synergism on anthropogenic CO emissions, which can be co-reduced with air pollutants.
View Article and Find Full Text PDFThis study was conducted to evaluate the efficacy of a combination 3,4,5-trihydroxybenzoic acid (THB) and oregano extracts (i.e., Carvacrol and Thymol) at intake/dietary different levels on growth performance, intestinal health indicators, immune responses and fecal oocyst shedding in broiler chickens under challenged condition.
View Article and Find Full Text PDFThe effect of Multi-Carbohydrase (MC) supplementation on growth performance, visceral organ weights, blood metabolites, jejunum morphology, nutrient digestibility, and carcass parameters of broiler chickens fed nutrient-deficient corn soybean-meal based diets containing high levels of non-starch polysaccharides from wheat and wheat by-products was investigated. A total of 378 one-day-old Ross 308 broiler chickens were randomly assigned to one of seven dietary treatments to give six replicates per treatment (nine birds per pen). Dietary treatments were as follows: (1) positive control (PC; commercial standard diet); (2) negative control 1 (NC-1; PC-120 kcal/kg metabolizable energy); (3) NC-2 (PC-3% standardized ileal digestibility [SID] amino acids).
View Article and Find Full Text PDFA growing body of research documents that bullying victimization is associated with delinquent behavior. There is an increasing need to better illuminate the factors that might moderate this relationship. This study examined whether the motivation to move out of low-resourced neighborhoods and sexual orientation/gender identity moderated the relationship between bullying victimization and delinquent behavior among a sample of 450 heterosexual and 91 non-heterosexual/cisgender African American youths.
View Article and Find Full Text PDFPurpose: This study was designed to explore the optimal minimum segment width (MSW) in the intensity-modulated radiotherapy (IMRT) plan for esophageal cancer.
Patients And Methods: The imaging data of 20 esophageal cancer patients were selected for this study. Four IMRT plans were designed for each patient with MSWs of 0.
The methods with multi-sensor data fusion have been a remarkable way to improve the accuracy and robustness of bearing fault diagnosis under complicated conditions. However, most of the existing fusion models or methods belong to single fusion level and simple fusion structure is usually utilized, and the correlation and complementarity of information between multi-sensor data might be easily ignored. In order to improve the performance of fault diagnosis with multi-sensor data fusion, this paper proposes a novel model of multi-layer deep fusion network with attention mechanism (AMMFN).
View Article and Find Full Text PDFNon-clinical cardiovascular drug safety assessment is the main step in the progress of new pharmaceutical products. Cardiac drug safety testing focuses on a delayed rectifier potassium channel block and QT interval prolongation, whereas optogenetics is a powerful technology for modulating the electrophysiological properties of excitable cells. For this purpose, the blue light-gated ion channel, channelrhodopsin-2 (ChR2), has been introduced into isolated primary neonatal cardiomyocytes via a lentiviral vector.
View Article and Find Full Text PDFPurpose: To compare the dosimetric differences between intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) in the treatment of male and female thymoma.
Material And Methods: This single-institutional analysis included 20 patients with thymoma treated with RT between January 2017 and December 2020. Twenty patients were retrospectively planned for IMRT (IMRT1 with an average field angle of 216°, 288°, 0°, 72°,and 144°; IMRT2 with fan-shaped field angles of 280°, 320°, 0°, 40°, and 80°) and VMAT (VMAT1 with two arcs ranging form 280° to 80°,clockwise and then counterclockwise; VMAT2 with two 360° arcs).
Teen dating violence (TDV) and school violence (SV) are two major social problems in adolescence. Until recently, the antecedents of both TDV and SV have been analyzed largely independently of each other. This study analyses and compares the determinants of both TDV and SV, with a focus on physical violence.
View Article and Find Full Text PDFObjectives: Adolescents' exposure to violence between parents acts as a precursor to risky behaviors; however, empirical studies that examined the potential pathways from exposure to violence between parents to risky behaviors are rare. Consequently, the prevention and intervention strategies for risky sexual activities are limited without the identification of malleable mediators.
Methods: Mediators on the association between adolescent exposure to parental fighting and risky sexual activities are examined, which include internalizing behaviors, running away from home, and affiliation with risky peers.
The immunosuppressive, inflammatory microenvironment orchestrated by neutrophil extracellular traps (NETs) plays a principal role in pathogenesis of sepsis. Fibroblast growth factor-inducible molecule 14 (Fn14) has been established as a potential target for septic acute kidney injury (AKI), making further therapeutic benefits from combined NETs and Fn14 blockade possible. The concurrence of NETs and Fn14 in mice and patients with septic AKI were assessed by immunofluorescence, immunohistochemistry, enzyme-linked immunosorbent assay (ELISA) and studies.
View Article and Find Full Text PDFBackground: We aimed to describe the effect of preoperative sarcopenia on oncologic outcomes of organ-confined renal cell carcinoma (RCC) after radical nephrectomy.
Patients And Methods: A total of 632 patients with pT1-2 RCC who underwent radical nephrectomy between 2004 and 2014 were retrospectively analyzed. From preoperative computerized tomography (CT) scans, skeletal muscle index (SMI) was measured and gender-specific cutoff values at third lumbar vertebra of 52.
The present study explored racial/ethnic and sex differences in fathers' awareness and perceived ease of communication with fathers and how they are related to adolescent bullying victimization and psychosomatic symptoms. Data were drawn from the 2009 to 2010 Health Behavior in School-Aged Children study in the United States. The sample consists of 5,121 White, 1,497 African American, and 1,850 Hispanic adolescents in grades 5 to 10.
View Article and Find Full Text PDFTaking the influence of alloying elements into consideration, a hardness prediction model based on a newly proposed parameter named actual carbon diffusion time (ACDT), which was calculated by combining temperature history with carbon diffusivity, is developed in this paper. The hardness distribution was directly derived from a 3D thermal model, which was constructed to simulate the laser surface hardening of AISI 1045, and from which the temperature history was also obtained. Using this 3D thermal model, the geometric characteristics after laser hardening (e.
View Article and Find Full Text PDFSirtuins are a family of NAD -dependent deacetylases implicated in a wide variety of age-associated pathologies, including cardiovascular disorders. Among the seven mammalian sirtuins, SIRT2 modulates various cellular processes through the deacetylation or deacylation of their target proteins. Notably, the levels of SIRT2 in the heart decline with age and other pathological conditions, leading to cardiovascular dysfunction.
View Article and Find Full Text PDFThe porous oil-containing cage achieves the storage, spillage, and suction of lubricating oil by its micro-pore structure, thus ensuring the self-lubricating performance of the bearing. Carrying out fast and accurate modeling of the cage microscopic pore structure is the key to the analysis of the self-lubricating mechanism of bearings. In response to the issues where current modeling methods of porous materials have a low similarity of pore distribution, morphology, structure, and size characteristics, and the transition of pore surfaces is sharp, this paper proposed a modeling method of a highly similar micro-pore structure based on the idea of median filtering, the quartet structure generation set (QSGS), and the slice method.
View Article and Find Full Text PDFAcute kidney injury (AKI) is related to mortality and morbidity. The De Ritis ratio, calculated by dividing the aspartate aminotransferase by the alanine aminotransferase, is used as a prognostic indicator. We evaluated risk factors for AKI after radical retropubic prostatectomy (RRP).
View Article and Find Full Text PDFWe tested a proposed conceptual framework in which we hypothesized that witnessing parental intimate partner violence (witnessing parental IPV) is linked to children's bullying and peer victimization. We also hypothesized that the relationship between witnessing parental IPV and bullying and peer victimization in childhood would be mediated by increased psychological problem behavior, school absences, and problematic peer interactions. We utilized data from the National Survey of Children's Health.
View Article and Find Full Text PDFlncRNAs play important roles in lipopolysaccharide- (LPS-) induced acute lung injury. But the mechanism still needs further research. In the present study, we investigate the functional role of the lncRNA-SNHG14/miR-223-3p/Foxo3a pathway in LPS-induced ALI and tried to confirm its regulatory effect on autophagy.
View Article and Find Full Text PDFAdolescent bullying continues to be a major focus of scholarship across the globe. This article reviews research from 2010 to 2021 with a particular focus on longitudinal studies of the (), where bullying serves as a precursor for sexual violence (SV) (e.g.
View Article and Find Full Text PDFIn this study, we investigated the mechanisms through which astrocyte-derived exosomes (AS-Exos) alleviate traumatic brain injury (TBI)-induced neuronal defects in TBI model rats and mice. Treatment with AS-Exos alleviated neurobehavioral deficits, cognitive impairment, and brain edema in TBI rats. AS-Exos also significantly reduced neuronal cell loss and atrophy in the TBI rats.
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