Publications by authors named "Holzgreve H"

Aim: We determined the effect of wearing clothes under the manometer's cuff on blood pressure in manual auscultatory sphygmomanometric and automatic oscillometric blood pressure measurement.

Methods: Two hundred and one subjects were examined with the auscultatory sphygmomanometric and the automatic oscillometric method, each with and without sleeved arm in random order. The auscultatory readings were blinded for the subjects' state of clothing.

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Monotherapy is able to normalize blood pressure in less than a quarter of patients with hypertension. However, for a disease of multifactorial pathogenesis like essential hypertension, a therapeutic strategy employing different principles of actions is most suitable. In addition, combination therapy has many advantages.

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Background: There is evidence that diuretics and beta blockers impair glucose tolerance, whereas calcium channel blockers and angiotensin converting enzyme blockers lack this metabolic effect. We compared the effect of a combination therapy with a nondihydropyridine calcium channel blocker plus an angiotensin converting enzyme inhibitor and a beta blocker plus a diuretic on hemoglobin A(1c) (Hb A(1c)) in patients with type 2 diabetes and mild-to- moderate hypertension.

Methods: A total of 463 hypertensive outpatients with non-insulin treated type 2 diabetes on stable antidiabetic therapy for at least 3 months and with HbA(1c) between 6.

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