Publications by authors named "Holubar J"

We conducted a national in-depth analysis including pharmacovigilance reports and clinical study to assess the reporting rate (RR) and to determine the clinical profile of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in COVID-19-vaccinated individuals. First, based on the French pharmacovigilance database, we estimated the RR of PMR and GCA cases in individuals aged over 50 who developed their initial symptoms within one month of receiving the BNT162b2 mRNA, mRNA-1273, ChAdOx1 nCoV-19, and Ad26.COV2.

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Introduction: Internal medicine departments manage patients referred by emergency departments or private practitioners. Considering the overcrowding of emergency departments and lack of beds for inpatients, this specialty must be part of an "ambulatory shift", particularly by strengthening the links between community and hospital medicine. Our objective was to evaluate a new care pathway in internal medicine at Nîmes university hospital.

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Objectives: Giant cell arteritis (GCA) is associated with severe outcomes such as infections and cardiovascular diseases. We describe here the impact of GCA patients’ characteristics and treatment exposure on the occurrence of severe outcomes. Methods: Data were collected retrospectively from real-world GCA patients with a minimum of six-months follow-up.

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Background: Inflammation of unknown origin (IUO) is a challenging situation in internal medicine.

Objectives: To describe the final diagnoses in IUO and assess the helpfulness of F-fluorodesoxyglucose positron emission tomography with computerized tomography ( F-FDG-PET/CT) in the diagnosis strategy.

Results: A total of 317 IUO patients with F-FDG-PET/CT were enrolled.

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Dilatation of distal urethral stenoses is one of the relatively frequent minor operations in child urology. The authors present a group of 830 female patients age 2-16 years treated by dilatation of the urethra in 1988-1994. According to the predominating finding they divide the cases into three groups--vesicoureteral reflux (VUR), infection of the urinary pathways (IUP), enuresis--and in these they evaluate the effectiveness of the operation, which was greatest in the group of patients with IUP (37%).

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The authors present the evaluation of some most often methods of treatment of trochanteric fractures of femur. They analyze the group of 235 patients in the years 1987 - 1991 treated for fractures by the McLaughlin technique and by Ender nailing. The first method was performed on 121 people and the technique of Ender nailing on 97 people.

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In the presented retrospective study the authors evaluate the effect of dilatation of the urethra in the treatment of relapsing infections of the urinary pathways in girls. In 1982-1987 at the Clinic of Paediatric Surgery in Brno 387 girls with infections of the urinary pathways were examined, in 112 stenosis of the distal urethra was found, in 24 moreover vesicoureteral reflux and 40 suffered from enuresis. After dilatation of the urethra, the technique of which is described in detail the urinary findings were normal in 83% of the girls and in more than half significant or complete regression of the vesicoureteral reflux was noted, in more than two thirds enuresis was eliminated.

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