Publications by authors named "Holly Philbrick"
Front Mol Biosci
August 2021
Article Synopsis
- Metabolomics is revealing new insights into disease mechanisms, especially when using different analytical methods to cover more of the metabolome and confirm findings.
- A study compared multisegment injection-capillary electrophoresis-mass spectrometry (MSI-CE-MS) and nuclear magnetic resonance (NMR) spectroscopy to analyze serum metabolites in hepatitis C patients and controls, finding a good overlap in detected metabolites.
- The research identified specific metabolite markers, like elevated choline and histidine, that distinguish the severity of liver fibrosis in HCV patients and showed correlations with liver stiffness measurements, indicating the potential for these biomarkers in clinical settings.
