Epidermolytic acanthoma of the scrotum: A rare mimicker of condyloma acuminatum.

Epidermolytic acanthoma is a rare benign tumor that is characterized by epidermolytic hyperkeratosis on histopathology. Epidermolytic acanthoma usually presents in adulthood as an asymptomatic tumor less than 1 cm in diameter with a verrucous surface. Whereas the lesions can present in either an isolated solitary, localized, or disseminated form, there tends to be a predilection for the genitoscrotal area.

Hybrid capture 2 human papillomavirus DNA testing for women with atypical squamous cells of undetermined significance Papanicolaou results in SurePath and ThinPrep specimens.

Background: Human papillomavirus (HPV) DNA testing using Hybrid Capture 2 assay with ThinPrep Papanicolaou (Pap) collection is the only US Food and Drug Administration-approved method for the triage of women with atypical squamous cells of undetermined significance (ASCUS). Although SurePath Pap collection has been used for Hybrid Capture 2 HPV DNA testing, clinical validation of this method has been scarce.

Methods: From a cervical cancer-screening program in Mississippi, we analyzed data from screenings of 8380 women with ASCUS Pap results who underwent reflex Hybrid Capture 2 HPV DNA tests during a course of 4 years.

Serial monitoring of humoral antibody-mediated rejection of cardiac allografts by C4d staining of interstitial capillaries.

C4d "staining" of interstitial capillaries of endomyocardial biopsies serves as an indicator of a humoral component of cardiac allograft rejection. In the present study, two cardiac allograft recipients were monitored serially for both cellular and humoral rejection. Cellular rejection, evaluated by light microscopy, and humoral rejection, judged by C4d immunofluorescent "staining", were treated with appropriate immunosuppressants.