Increased extracellular vesicles mediate inflammatory signalling in cystic fibrosis.

Rationale: Mutations in the cystic fibrosis transmembrane regulator () gene form the basis of cystic fibrosis (CF). There remains an important knowledge gap in CF as to how diminished CFTR activity leads to the dominant inflammatory response within CF airways.

Objectives: To investigate if extracellular vesicles (EVs) contribute to inflammatory signalling in CF.