Publications by authors named "Holly Baker-Rand"
Article Synopsis
- The guidelines are created by the British Gynaecological Cancer Society and British Menopause Society to help healthcare professionals support women treated for gynaecological cancer, especially regarding menopausal symptoms that can affect life quality.* -
- Cancer treatments like surgery, radiotherapy, and chemotherapy can impact hormonal function, and the guidelines discuss the use of hormone replacement therapy (HRT) based on cancer type and when it should start post-treatment.* -
- The document also highlights the effectiveness and safety of vaginal estrogens for urogenital symptoms and reviews alternative treatments to HRT, including both medication and lifestyle approaches.*
Recent Advances in Endometrial Cancer Prevention, Early Diagnosis and Treatment.
Cancers (Basel)
March 2024
Endometrial cancer is the sixth commonest cancer in women worldwide, with over 417,000 diagnoses in 2020. The disease incidence has increased by 132% over the last 30 years and is set to continue to rise in response to an ageing population and increasing global rates of obesity and diabetes. A greater understanding of the mechanisms driving endometrial carcinogenesis has led to the identification of potential strategies for primary disease prevention, although prospective evaluation of their efficacy within clinical trials is still awaited.
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- - The study investigates how healthcare practitioners in the UK and Ireland assess and manage frailty in patients with gynecological cancers, highlighting a disparity in practices across different care settings.
- - Data from a survey of 206 professionals indicated that 63% of settings don’t routinely perform frailty scoring, even though most practitioners adjust their care based on frailty levels.
- - Conclusions suggest a need for better training, specific pathways for frailty management, and standardized performance indicators to improve care for these vulnerable patients.
Study Design: Biomechanical and radiographical study on cadaveric spines.
Objective: To explain the pathogenesis of vertebral "anterior wedge" deformity, which causes senile kyphosis.
Summary Of Background Data: This deformity arises with minimal trauma and is difficult to reproduce in cadaveric spines.
Background Context: The vertebral augmentation procedures, vertebroplasty and kyphoplasty, can relieve pain and facilitate mobilization of patients with osteoporotic vertebral fractures. Kyphoplasty also aims to restore vertebral body height before cement injection and so may be advantageous for more severe fractures.
Purpose: The purpose of this study was to compare the ability of vertebroplasty and kyphoplasty to restore vertebral height, shape, and mechanical function after severe vertebral wedge fractures.