Treatment of venous thromboembolism in ambulatory cancer patients in Germany: a prospective non-interventional study.

Background: Venous thromboembolism (VTE) is a serious threat for all cancer patients. This study was aimed to assess the VTE treatment of cancer patients in the ambulatory care setting.

Patients And Methods: This is a prospective non-interventional study, which includes ambulatory cancer patients from office-based oncologists.

Evidence for less irritation to the peritoneal membrane in rats dialyzed with solutions low in glucose degradation products.

Background: Acidic pH and the presence of glucose degradation products (GDP) are believed to compromise the biocompatibility of peritoneal dialysis fluids (PDF). The present study examines the effects of long-term exposure to GDP and low pH by comparing conventional PDF and a new, neutral pH, low GDP solution.

Methods: All experiments were performed using a chronic infusion model of dialysis in nonuremic rats.

Characteristics of hypotension-prone haemodialysis patients: is there a critical relative blood volume?

Background: Intradialytic morbid events (IME, mostly hypotension) mainly due to ultrafiltration-induced hypovolaemia still are the most frequent complication during haemodialysis (HD). This study was performed to test the hypothesis that there is an individual critical relative blood volume (RBV(crit)) in IME-prone HD patients.

Methods: In this prospective international multicentre study, 60 IME-prone patients from nine dialysis centres were observed during up to 21 standard HD sessions without trial-specific intervention.