Implementation of a Medication Reconciliation Assistive Technology: A Qualitative Analysis.

: To aid the implementation of a medication reconciliation process within a hybrid primary-specialty care setting by using qualitative techniques to describe the climate of implementation and provide guidance for future projects. : Guided by McMullen et al's Rapid Assessment Process, we performed semi-structured interviews prior to and iteratively throughout the implementation. Interviews were coded and analyzed using grounded theory and cross-examined for validity.

Beyond technology acceptance to effective technology use: a parsimonious and actionable model.

Objective: To develop and test a parsimonious and actionable model of effective technology use (ETU).

Design: Cross-sectional survey of primary care providers (n = 53) in a large integrated health care organization that recently implemented new medication reconciliation technology.

Methods: Surveys assessed 5 technology-related perceptions (compatibility with work values, implementation climate, compatibility with work processes, perceived usefulness, and ease of use) and 1 outcome variable, ETU.

Influence of drift and admixture on population structure of American black bears (Ursus americanus) in the Central Interior Highlands, USA, 50 years after translocation.

Bottlenecks, founder events, and genetic drift often result in decreased genetic diversity and increased population differentiation. These events may follow abundance declines due to natural or anthropogenic perturbations, where translocations may be an effective conservation strategy to increase population size. American black bears (Ursus americanus) were nearly extirpated from the Central Interior Highlands, USA by 1920.

Primary care provider perceptions and use of a novel medication reconciliation technology.

Background: Although medication reconciliation (MR) can reduce medication discrepancies, it is challenging to operationalise. Consequently, we developed a health information technology (HIT) to collect a patient medication history and make it available to the primary care (PC) provider. We deployed a self-service kiosk in a PC clinic that permits patients to indicate a medication adherence history.

Psychological antecedents of escalation behavior: effects of choice, responsibility, and decision consequences.

Research on escalation behavior has proposed that choice of an initial course of action, responsibility for decision outcomes, and negative decision consequences are necessary conditions for the escalation effect to occur. This proposition was tested in a sample of 257 undergraduates. Results show that although responsibility and negative decision consequences contribute to the escalation effect, they are not necessary conditions for escalation to occur.

Hyperthermic effects on viability and growth kinetics of human lymphoblastoid cells.

During clinical hyperthermia, various blood elements may be exposed to elevated temperatures. The effect of heat on human lymphocyte viability and human lymphoblastoid cell viability and growth was therefore measured. In the viability studies, cells were heated for different times and temperatures and stained with fluorescein diacetate either immediately of at various times after treatment; dye uptake was then analysed using fluorescence microscopy.

Alterations in phosphate metabolism during cellular recovery of radiation damage in yeast.

We have examined alterations in phosphate pools during cellular recovery from radiation damage in intact, wild-type diploid yeast cells using 31P nuclear magnetic resonance (NMR) spectroscopy. Concurrent cell survival analysis was determined following exposure to 60Co gamma-radiation. Cells held in citrate-buffered saline (CBS) showed increased survival with increasing time after irradiation (liquid holding recovery, LHR) with no further recovery beyond 48 h.

Hyperthermic radiosensitization of thermotolerant Chinese hamster ovary cells.

Synchronous G1 cells were given a priming dose of heat (45.5 degrees C for 15 min) and then heated and irradiated 6-120 h later. Compared to heat radiosensitization for cells irradiated 10 min after the priming heat dose (thermal enhancement ratio, TER of 2.

Survival of heated or irradiated Chinese hamster ovary microcolonies that develop after an initial dose of heat.

Asynchronous or synchronous G1 cells were heated initially and then heated or irradiated a second time when the multiplicity of viable cells in microcolonies that developed from cells surviving the first heat dose had increased to 6-30. The survival of these microcolonies was compared with the survival of single cells that were heated or irradiated after the microcolonies had been trypsinized and dispersed into single cells. The survival of the single cells was similar to the survival of the microcolonies and much higher than single cell survival calculated by correcting microcolony survival for multiplicity.

Effect of pH and cell cycle progression on development and decay of thermotolerance.

Synchronous Chinese hamster ovary cells were heated in G1 and incubated at 37 degrees C at pH 6.75 or pH 7.4 before they were heated a second time.

Hyperthermic killing and hyperthermic radiosensitization in Chinese hamster ovary cells: effects of pH and thermal tolerance.

To quantitatively relate heat killing and heat radiosensitization, asynchronous or G1 Chinese hamster ovary (CHO) cells at pH 7.1 or 6.75 were heated and/or X-irradiated 10 min later.

Hyperthermic survival of Chinese hamster ovary cells as a function of cellular population density at the time of plating.

The survival of synchronous G1 or asynchronous Chinese hamster ovary cells in vitro to heat treatment may depend on the cellular population density at the time of heating and/or as the cells are cultured after heating. The addition of lethally irradiated feeder cells may increase survival at 10(-3) by as much as 10- to 100-fold for a variety of conditions when cells are heated either in suspension culture or as monolayers with or without trypsinization. The protective effect associated with feeder cells appears to be associated with close cell-to-cell proximity.