Publications by authors named "Hoeve-Bakker B"
Lyme borreliosis (LB) is not notifiable in many European countries, and the patchwork of surveillance strategies in Europe perpetuates knowledge gaps. In the Netherlands, LB incidence has been estimated from recurring general practitioner surveys since the 1990s. To complement the incidence data, this study aimed to estimate the prevalence of antibodies against sensu lato in the general population of the Netherlands in 1995/1996, identify risk factors for seropositivity, and compare these findings to data from 2016/2017 to identify temporal trends.
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- The study looked at different testing methods for diagnosing Lyme disease, focusing on two strategies: standard (STTT) and modified (MTTT).
- Both testing strategies were used on patients with Lyme neuroborreliosis (LNB) and Lyme arthritis (LA) to see how well they worked.
- The results showed that the modified strategy was slightly better in finding Lyme disease without losing accuracy, making it a good choice for doctors to use.
Seropositivity to tick-borne pathogens in nature management workers in the Netherlands.
Ticks Tick Borne Dis
September 2024
The incidence of tick-borne infections other than Lyme borreliosis and tick-borne encephalitis is rising in Europe, including the Netherlands. Nature management workers, being highly exposed to ticks, serve as valuable sentinels for seroprevalence studies on tick-borne pathogens (TBPs). This study assessed nature management workers' seropositivity to TBPs including Anaplasma phagocytophilum, Babesia divergens, B.
View Article and Find Full Text PDFLyme borreliosis (LB) is not notifiable in many European countries, and accurate data on the incidence are often lacking. This study aimed to determine the seroprevalence of sensu lato (s.l.
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- The text discusses a zoonotic bacterium that is widespread globally but is not included in common mass spectrometry identification systems, specifically Vitek MS and Bruker Biotyper.
- It highlights that the bacterium’s virulence varies among its subspecies, with some being highly pathogenic and others showing low or nearly no virulence.
- An in-house library was developed and validated to differentiate the subspecies accurately, enhancing clinical diagnostics through specific biomarkers and MALDI-TOF MS technology.
Background: The extent to which infections with -borne pathogens (TBPs), other than s. l. and tick-borne encephalitis virus (TBEV), cause disease in humans remains unclear.
View Article and Find Full Text PDFLaboratory diagnosis of Lyme neuroborreliosis (LNB) is challenging, and validated diagnostic algorithms are lacking. Therefore, this retrospective cross-sectional study aimed to compare the diagnostic performance of seven commercial antibody assays for LNB diagnosis. Random forest (RF) modeling was conducted to investigate whether the diagnostic performance using the antibody assays could be improved by including several routine cerebrospinal fluid (CSF) parameters (i.
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- A retrospective study assessed the effectiveness of nine serological assays for diagnosing Lyme borreliosis (LB) using sera from 74 LB cases and 122 controls.
- Sensitivity of these tests varied significantly, with higher detection rates in cases like Lyme neuroborreliosis compared to early Lyme cases, and overall performance was adequate across both early and late forms of LB.
- The study concluded that while serological assays are essential for diagnosing LB, IgM testing did not enhance diagnostic accuracy beyond IgG testing, and a two-tier testing approach is recommended to minimize false positives.
spp. and entero-invasive (EIEC) can cause mild diarrhea to dysentery. In Netherlands, although shigellosis is a notifiable disease, there is no laboratory surveillance for spp.
View Article and Find Full Text PDFThe reported prevalence of Sarcocystis infection in cattle in Europe ranges between 66 and 94%. Although in the Netherlands a prevalence of 100% was reported in 1993, this study aimed to develop a method for sensitive and specific molecular detection and species identification of Sarcocystis spp., in order to provide more recent data on the prevalence and identification of these protozoa in cattle meat intended for human consumption in the Netherlands.
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