A new era in cystic fibrosis care: always changing and adapting.

Purpose Of Review: This review focuses on sharing the current and changing cystic fibrosis (CF) care model. This includes changes in CF care as a chronic disease with availability of new revolutionary, highly effective therapies as well as incorporation of shared decision-making, coproduction of care, quality improvement, telemedicine, and remote patient monitoring.

Recent Findings: Changes in the CF management, the CF patient population, and CF care team are described as well as how CF care has adapted to these changes.

A Single-Day Training for Managers Reduces Cognitive Stigma Regarding Mental Health Problems: A Randomized Trial.

Background: Mental illnesses have received increasing attention in the work context in recent years, yet they are still often accompanied by stigma. One starting point for stigma reduction is interventions in the workplace. The present study evaluated a one-day workshop for managers in a large company.

Long-Term Attitude Change After a Single-Day Manager Training Addressing Mental Health at the Workplace.

Mental health problems have become one of the most common causes of incapacity for work, and engender high costs to society. Especially managerial behavior was found to have a great impact on employees' well-being. In order to support those in leading positions in dealing with their own, as well as their employees', psychological stress factors, we conducted a specific manager training.

The effects of the SUN project on teacher knowledge and self-efficacy regarding biological energy transfer are significant and long-lasting: results of a randomized controlled trial.

Biological energy flow has been notoriously difficult to teach. Our approach to this topic relies on abiotic and biotic examples of the energy released by moving electrons in thermodynamically spontaneous reactions. A series of analogical model-building experiences was supported with common language and representations including manipulatives.

"Psychosomatic consultation in the workplace": a new model of care at the interface of company-supported mental health care and consultation-liaison psychosomatics: design of a mixed methods implementation study.

Background: Mental health issues are gaining in importance in society and the economic system. At the same time, the accessibility and stigmatisation of the mental health care system in Germany can obstruct help-seeking behavior and delay early psychotherapeutic interventions. Therefore, new models of care are being established at the interface of company-supported health promotion and conventional health insurance sponsored outpatient care for people developing mental illnesses.

The evolutionary history of the sinica-group of macaque monkeys as revealed by mtDNA restriction site analysis.

We estimated the phylogenetic relationships of mitochondrial DNA haplotypes within the sinica-group of macaques, which includes Macaca sinica, M. radiata, M. thibetana, M.

DNA repair and the evolution of transformation in Bacillus subtilis. III. Sex with damaged DNA.

Natural genetic transformation in the bacterium Bacillus subtilis provides an experimental system for studying the evolutionary function of sexual recombination. The repair hypothesis proposes that during transformation the exogenous DNA taken up by cells is used as template for recombinational repair of damages in the recipient cell's genome. Earlier results demonstrated that the population density of transformed cells (i.

A computer-assisted quality assurance audit in a multiprovider EMS system.

Prehospital care delivered by multiple agencies and their paramedics in a suburban emergency medical services (EMS) system was compared to assess the impact of a receiving hospital quality assurance audit on paramedic and agency performance. A committee of physicians, nurses, and paramedics developed performance criteria based on a county EMS protocol. Run tapes were reviewed to assess accuracy of runsheets.

DNA repair and the evolution of transformation in Bacillus subtilis. II. Role of inducible repair.

In Bacillus subtilis, DNA repair and recombination are intimately associated with competence, the physiological state in which the bacterium can bind, take up and recombine exogenous DNA. Previously, we have shown that the homologous DNA transformation rate (ratio of transformants to total cells) increases with increasing UV dosage if cells are transformed after exposure to UV radiation (UV-DNA), whereas the transformation rate decreases if cells are transformed before exposure to UV (DNA-UV). In this report, by using different DNA repair-deficient mutants, we show that the greater increase in transformation rate in UV-DNA experiments than in DNA-UV experiments does not depend upon excision repair or inducible SOS-like repair, although certain quantitative aspects of the response do depend upon these repair systems.

DNA repair and the evolution of transformation in the bacterium Bacillus subtilis.

The purpose of the work reported here is to test the hypothesis that natural genetic transformation in the bacterium Bacillus subtilis has evolved as a DNA repair system. Specifically, tests were made to determine whether transformation functions to provide DNA template for the bacteria] cell to use in recombinational repair. The survivorship and the homologous transformation rate as a function of dose of ultraviolet irradiation (UV) was studied in two experimental treatments, in which cells were either transformed before (DNA-UV), or after (UV-DNA), treatment with UV.

Recent advances in intravenous therapy.

For trauma resuscitation, the American College of Surgeons Committee on Trauma recommends at least two large-bore intravenous lines for rapid fluid administration. Access to venous circulation may be difficult and challenging in emergency situations. The physician should be accomplished in numerous intravenous access techniques.

Clinical findings and legal resolution in sexual assault.

Female sexual assault victims who received medical evaluation at Detroit Receiving Hospital from July to December 1980 and were seen by the Rape Counseling Center (RCC) were evaluated. Data were abstracted from the emergency department record, RCC file, and gynecology clinic; 372 patients were evaluated. One hundred twenty-seven patients (34%) were given DES, including 17 women who had been raped at least once before.

Electrophysiologic and antiarrhythmic effects of nitroglycerin in man.

The electrophysiologic properties and the arrhythmic disposition of the human heart were determined in 16 patients before and after the intravenous administration of nitroglycerin (0.25 and 0.50 micrograms/kg/min).