Phthisis bulbi: clinical and pathologic findings in retinoblastoma.

Purpose: Phthisis bulbi represents an ocular end-stage disease characterized by shrinkage and disorganization of the eye. We aim at identifying the pathologic changes of phthisis bulbi associated with retinoblastoma.

Design: Retrospective observational case series study.

Metachronous aneurysmal bone cyst in a 9-year-old boy: case report and review of the literature.

Aneurysmal bone cyst (ABC) is a locally aggressive, benign bone tumor that commonly affects children. Metachronous ABCs are rare, and have been described only three times in the literature. Here we present a fourth case in a 9-year-old boy who presented with an ABC of the scapula; 2½ years later he presented with a tibial ABC.

Chorangioma and related vascular lesions of the placenta--a review.

Chorangioma has been referred to as a hamartoma-like, or a hyperplastic capillary lesion, rather than a true neoplasm. Its incidence is 1 in 100 placentas. In chorangiomas larger than 4 cm, there can be significant effects on the hemodynamic and circulatory processes of the fetus, leading to grave clinical consequences, such as polyhydramnios and fetal heart failure.

Intraosseous benign notochordal cell tumor.

Intraosseous benign notochordal cell tumor is a presumably benign, intravertebral lesion of notochord origin, which can be found incidentally on removal of the vertebra for unrelated lesions or during an autopsy. The notion of a larger benign notochordal cell tumor that is macroscopic, occasionally symptomatic, and seen radiologically was recently introduced, and described as giant vertebral notochordal rest, giant notochordal hamartoma of intraosseous origin, and benign chordoma . Because of the location, size, and similar histologic and immunohistochemical characteristics, larger benign notochordal cell tumors are easily misdiagnosed as the malignant notochord-type of tumor/chordoma, with critical implications.

Cellular angiofibroma is genetically similar to spindle cell lipoma: a case report.

Cellular angiofibroma is a benign mesenchymal neoplasm of female and male genital tract composed of prominent vasculature and stromal spindle cells, often with admixture of adipose tissue. The tumor has histomorphologic similarities to angiomyofibroblastoma and spindle cell lipoma. Herein we describe a tumor arising in the perineal region of a 60-year-old man with morphological and immunohistochemical features of cellular angiofibroma and showing cytogenetic characteristics similar to spindle cell lipoma.

Infarcted ectopic spleen presenting as retroperitoneal mass.

Wandering or ectopic spleen is an exceptionally rare condition. Because of the abnormally long pedicle, an ectopic spleen is prone to torsion and infarction. Patients can present with abdominal pain or an acute abdomen.