Publications by authors named "Hoda Taheri"
Article Synopsis
- Researchers evaluated the effectiveness of various insulin resistance (IR) and sensitivity (IS) measures in identifying metabolic-associated fatty liver disease (MAFLD) and liver fibrosis in a cross-sectional study involving 644 individuals aged 25-75.
- The study found that 49.7% of participants had MAFLD, and 12.4% had significant liver fibrosis, with TyG-WC, TyG-BMI, and TyG-WHtR emerging as the top indicators for MAFLD detection.
- Additionally, insulin-based measures like HOMA-IR and QUICKI performed best in identifying liver fibrosis across different demographic groups, regardless of age, gender, obesity, or diabetes status.
Article Synopsis
- The article discusses a new method for simultaneously detecting arginine and valine amino acids in plasma using innovative flower-shaped microfluidic devices (μPADs) and a hybrid chip made of PMMA and paper, enhanced with gold nanoparticles (AuNPs).
- The detection process utilizes a smartphone colorimetric approach that visually indicates amino acid presence by changing color from red to blue, showing good reproducibility and a linear relationship between absorbance and concentration.
- This method offers several advantages over traditional techniques, including lower costs, higher sensitivity, faster results, and the ability to process many samples at once, with effective detection limits for arginine and valine being 2.25 nM and 1.86 nM, respectively.
Smartphone-based microfluidic chip modified using pyrrolidine-1-dithiocarboxylic acid for simultaneous colorimetric determination of Cr and Al ions.
Spectrochim Acta A Mol Biomol Spectrosc
May 2022
A portable µ-chip-based colorimetric device was developed for the determination of Cr and Al ions. The silver nanoparticles were modified with pyrrolidine-1-dithiocarboxylic acid ammonium salt as a novel ligand for the first time. The color of modified AgNPs in the test zone immediately changes after the addition of Cr and Al ions.
View Article and Find Full Text PDFThe triglyceride glucose (TyG) index has been proposed as a reliable surrogate marker for nonalcoholic fatty liver disease (NAFLD). Furthermore, NAFLD is strongly related with obesity. This study aimed to compare TyG index and its related parameters (TyG-waist circumference [WC] and TyG-body mass index [BMI]), comprising TyG and obesity markers, in predicting NAFLD and liver fibrosis in overweight/obese individuals without diabetes.
View Article and Find Full Text PDFIntroduction: Despite the high prevalence of non-alcoholic fatty liver disease (NAFLD) and its associated co-morbidities, no efficient treatment in a high percentage of individuals is available. Beneficial effects of sodium-glucose co-transporter 2 inhibitors on fatty liver have been investigated in people with type 2 diabetes (T2DM). The aim of this study was to explore the effect of empagliflozin on liver steatosis and fibrosis in patients with NAFLD without T2DM.
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