Antioxidant properties of the Lebanese plant x L. crude extracts and antagonism of chlorpromazine toxicity on .

x L., which belongs to the family, has been reported in the literature for its antioxidant properties in acellular chemical-antioxidant assays. Chlorpromazine (CPZ) is an antipsychotic drug known to cause adverse reactions in humans.

Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges.

Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7).

New alkaloids from Daphniphyllum calycinum.

Four new alkaloids, 17-hydroxyhomodaphniphyllic acid (1), daphcalycinosidine C (2, a new iridoid alkaloid), yuzurimine E (3), and yuzurimic acid B (4), were isolated from the seeds of Daphniphyllum calycinum. The structures of these Daphniphyllum alkaloids were determined by spectroscopic analysis including mass spectrometry and 2D NMR.

Daphcalycine, a novel heptacycle fused ring system alkaloid from Daphniphyllum calycinum.

A novel Daphniphyllum alkaloid, daphcalycine (1), was isolated together with known daphnicyclidin D (2) from the stem bark of Daphniphyllum calycinum. The highly condensed polycyclic structure, established by spectral analysis, possessed an unusual framework: a central quinuclidine like tricycle produced by fusion of a piperidine, a tetrahydropyran, and an oxazine ring in turn condensed to surrounding three penta-, one hexa-, and one hepta-membered rings. The relative configuration of 11 carbon stereocenters of 1 was elucidated on the basis of NOESY.