Publications by authors named "Hoda El Assi"
Background: Obesity is attributed to a combination of factors such as lifestyle, environmental influences, and genetic background. Nowadays, the issue of obesity has grown to an epidemic scale. Environmental changes, having contributed to the sharp rise in obesity prevalence, are not the only contributing etiologic factors.
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- Glomerulonephritis (GN) is a complicated kidney disease linked to issues with the immune system, and its relationship with complement dysregulation needs more research, especially in autoimmune and infection cases.
- A study focused on lupus nephritis (LN) and post-infectious GN (PIGN), identifying several pathogenic and likely pathogenic gene variants in complement regulating genes, particularly noting a novel variant found prominently in patients from the Egyptian population.
- The discovery of these variations suggests that minor genetic mutations may worsen GN disease progression, highlighting the need for additional research on how these gene variants influence patient outcomes and disease severity.