Effectiveness and safety of bedaquiline-based, modified all-oral 9-11-month treatment regimen for rifampicin-resistant tuberculosis in Vietnam.

Objectives: World Health Organization recommends a 7-drug 9-11-month rifampicin-resistant tuberculosis (RR-TB) short treatment regimen (STR). To reduce the pill burden, we assessed the safety and effectiveness of a 5-drug 9-11-month modified STR (mSTR).

Methods: Prospective cohort study of an all-oral mSTR (comprising bedaquiline, levofloxacin, linezolid [LZD], clofazimine, and/or pyrazinamide) for patients with RR-TB without confirmed fluoroquinolone resistance, enrolled in Vietnam between 2020-2021.

Safety and effectiveness of all-oral and injectable-containing, bedaquiline-based long treatment regimen for pre-XDR tuberculosis in Vietnam.

The World health organization (WHO) recently recommended standardized all-oral shorter regimens for rifampicin resistant Tuberculosis (RR-TB). For highly resistant Tuberculosis patients such as pre-XDR-TB: RR-TB plus additional resistance to fluoroquinolones (FQ), the 6-9-months bedaquiline (bedaquiline)-based regimens or BDQ-based long regimens are recommended. The role of second-line injectable (SLI) drugs in the treatment of drug resistant TB is restricted because of safety concerns.

Spatial and temporal variations of PAHs in surface sediments of estuarine and coast of CanGio wetland, Vietnam.

Surface sediments from estuarine and coast of CanGio wetland (CGW) of Hochiminh City, Vietnam, were investigated to identify the spatial and temporal variations of polycyclic aromatic hydrocarbons (PAHs). The total PAHs showed wide variation but similar to patterns observed (F = 0.901, p = 0.

Does sunlight drive seasonality of TB in Vietnam? A retrospective environmental ecological study of tuberculosis seasonality in Vietnam from 2010 to 2015.

Background: Tuberculosis (TB) is a major global health burden, with an estimated quarter of the world's population being infected. The World Health Organization (WHO) launched the "End TB Strategy" in 2014 emphasising knowing the epidemic. WHO ranks Vietnam 12th in the world of high burden countries.

Active contact tracing beyond the household in multidrug resistant tuberculosis in Vietnam: a cohort study.

Background: Currently in Vietnam contact tracing for multidrug-resistant tuberculosis (MDR-TB) entails passive case finding among symptomatic household contacts who present themselves for diagnosis. Close contacts of MDR-TB cases are therefore not identified adequately. We assessed the added value of active contact tracing within and beyond households using social network questionnaires to identify close contacts of MDR-TB patients in Vietnam.

The potential accumulation of polycyclic aromatic hydrocarbons in phytoplankton and bivalves in Can Gio coastal wetland, Vietnam.

Polycyclic aromatic hydrocarbons (PAHs) are one of the most important classes of anthropogenic persistent organic contaminants in the marine environment. This review discusses a whole range of findings that address various aspects of the bioaccumulation of PAHs in two common marine biota (phytoplankton and bivalves) globally and especially for Can Gio coastal wetland, Vietnam. The published information and collected data on the bioconcentration and accumulation mechanisms of PAHs as well as implications for Can Gio coastal wetland are compiled for phytoplankton and bivalves.

The potential environmental risks of pharmaceuticals in Vietnamese aquatic systems: case study of antibiotics and synthetic hormones.

Presently, many pharmaceuticals are listed as emerging contaminants since they are considered to be great potential threats to environmental ecosystems. These contaminants, thus, present significant research interest due to their extensive use and their physicochemical and toxicological properties. This review discusses a whole range of findings that address various aspects of the usage, occurrence, and potentially environmental risks of pharmaceuticals released from various anthropogenic sources, with emphasis on the aquatic systems in Vietnam.

Antibiotic contaminants in coastal wetlands from Vietnamese shrimp farming.

Background And Purpose: Shrimp culture has been expanded rapidly in recent years in coastal wetland zone of Vietnam due to favorable natural conditions. However, this industry has caused several negative impacts to the environment. One of the critical issues is the excessive application of antibiotics including human medicines.

Phytoremediation as a management option for contaminated sediments in tidal marshes, flood control areas and dredged sediment landfill sites.

Background, Aim And Scope: Polluted sediments in rivers may be transported by the river to the sea, spread over river banks and tidal marshes or managed, i.e. actively dredged and disposed of on land.