Publications by authors named "Hoang Q Tran Van"
Article Synopsis
- Hydrophobicity plays a key role in how amphipathic antimicrobial peptides interact with microbial pathogens, but it's influenced by other structural factors like peptide length and charge.
- The study compares three similar natural antimicrobial peptides—mastoparan C, mastoparan-AF, and mastoparan L—with varying levels of hydrophobicity, finding that mastoparan C has the highest hydrophobicity and helical content, leading to strong hemolytic activity.
- It concludes that an optimal level of hydrophobicity improves antimicrobial effectiveness while reducing harmful hemolytic activity, rather than simply maximizing hydrophobicity.
