A Molecular Biological and Biochemical Investigation on Mycobacterium tuberculosis MutT Protein.

Background: Mycobacterium tuberculosis is a vicious microbe co-existing with the infected host. This pathogen exploited opportunities to spread during periods of urbanization and social upheaval, and got retreated with improved hygiene.

Objectives: This investigation was designed to clone and characterize M.

Cross-linking of P-selectin glycoprotein ligand-1 induces death of activated T cells.

Increasing evidence has shown that death signaling in T cells is regulated in a complicated way. Molecules other than death receptors can also trigger T-cell death. Here, we demonstrate for the first time that P-selectin glycoprotein ligand-1 (PSGL-1) or CD162 molecules cross-linked by an anti-PSGL-1 monoclonal antibody, TAB4, can trigger a death signal in activated T cells.