Publications by authors named "Ho-Sang Leung"

Objective: To investigate the impact of cigarette consumption on mucosal thickening in paranasal sinuses and the relationships of smoking-related factors and dental status with mucosal thickening at different maxillary sinus locations using MRI.

Materials And Methods: This retrospective study investigated 1094 paranasal sinuses on MRIs by correlating mucosal thickening with smoking-related factors. Presence/absence of maxillary posterior teeth was correlated with mucosal thickening on the maxillary sinus floor and other sinus locations.

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Objectives: To investigate the potential of T1rho, a new quantitative imaging sequence for cancer, for pre and early intra-treatment prediction of treatment response in nasopharyngeal carcinoma (NPC) and compare the results with those of diffusion-weighted imaging (DWI).

Materials And Methods: T1rho and DWI imaging of primary NPCs were performed pre- and early intra-treatment in 41 prospectively recruited patients. The mean preT1rho, preADC, intraT1rho, intraADC, and % changes in T1rho (ΔT1rho%) and ADC (ΔADC%) were compared between residual and non-residual groups based on biopsy in all patients after chemoradiotherapy (CRT) with (n = 29) or without (n = 12) induction chemotherapy (IC), and between responders and non-responders to IC in the subgroup who received IC, using Mann-Whitney U-test.

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Article Synopsis
  • A study was conducted to evaluate a short, contrast-free MRI for detecting nasopharyngeal carcinoma (NPC) in patients screened positive for Epstein-Barr virus (EBV) DNA.
  • Among 354 patients, MRI identified additional NPC cases that were missed by endoscopy, with high sensitivity and specificity for detecting the cancer.
  • The results suggest that MRI can enhance NPC screening programs by finding cases that traditional methods might overlook, improving early detection and reducing the risk of missed diagnoses.
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Background: Little is known about the differences in medium to long-term recovery on spirometry, 6-minute walking distance (6MWD) and health-related quality of life (HRQoL) between COVID-19 and SARS.

Methods: We performed a 12-month prospective study on COVID-19 survivors. The changes in dynamic lung volumes at spirometry (%predicted FEV, %predicted FVC), 6MWD and HRQoL at 1-3, 6 to 12 months were compared against a historical cohort of SARS survivors using the same study protocol.

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Eagle jugular syndrome is an uncommon condition caused by compression of an elongated styloid process onto the internal jugular vein. Its presentation is non-specific but may represent in severe clinical consequences including venous thrombosis and intracranial haemorrhage. Thorough understanding of local anatomy is important in understanding the pathogenesis and establishing the diagnosis.

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  • People living with HIV (PLWH) are at a higher risk for cardiovascular diseases, leading to a need for better assessment tools since current models don't consider their specific risks.
  • A study was conducted involving 115 PLWH with cardiovascular risk factors, using advanced retinal image analysis alongside computerized tomography to evaluate coronary artery disease (CAD).
  • The research found that combined models using both retinal characteristics and traditional risk factors were significantly more effective in determining coronary atherosclerosis compared to traditional risk assessments alone, demonstrating high sensitivity and specificity.
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Pre-operative embolization of spinal tumours are mainly performed using a transarterial approach. Percutaneous embolization of spinal tumours are undertaken much less frequently, though its use has been reported in hypervascular spinal metastases and spinal paraganglioma. We present a patient in whom pre-operative percutaneous embolization has been performed to a recurrent lumbar nerve root haemangioblastoma that had previously been embolized using a transarterial approach.

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